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Serrate RNA Effector Molecule 抗体 (N-Term)

SE 适用: 人 WB, IHC (p), IP, ICC, IF 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7468958
发货至: 中国
  • 抗原 See all Serrate RNA Effector Molecule (SE) products
    Serrate RNA Effector Molecule (SE)
    抗原表位
    N-Term
    适用
    宿主
    • 1
    • 1
    克隆类型
    • 2
    多克隆
    标记
    • 2
    This Serrate RNA Effector Molecule antibody is un-conjugated
    应用范围
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
    交叉反应
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the N-terminus region of human ARS2. The exact sequence is proprietary.
    亚型
    IgG
  • 应用备注
    WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.76 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    Serrate RNA Effector Molecule (SE)
    别名
    serrate, RNA effector molecule (SE 产品)
    别名
    ARS2 antibody, ASR2 antibody, serrate antibody, SERRATE antibody, T20P8.15 antibody, T20P8_15 antibody, serrate, RNA effector molecule antibody, C2H2 zinc-finger protein SERRATE (SE) antibody, SRRT antibody, SE antibody
    背景

    Synonyms: serrate, RNA effector molecule , ARS2 , ASR2 , serrate

    Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.

    分子量
    101 kDa
    基因ID
    51593
    UniProt
    Q9BXP5
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