Serrate RNA Effector Molecule 抗体 (N-Term)
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- 抗原 See all Serrate RNA Effector Molecule (SE) products
- Serrate RNA Effector Molecule (SE)
- 抗原表位
- N-Term
- 适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Serrate RNA Effector Molecule antibody is un-conjugated
- 应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunocytochemistry (ICC), Immunofluorescence (IF)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the N-terminus region of human ARS2. The exact sequence is proprietary.
- 亚型
- IgG
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- 应用备注
- WB: 1:1000-1:20000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , A431 , HeLa , HepG2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.76 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- Serrate RNA Effector Molecule (SE)
- 别名
- serrate, RNA effector molecule (SE 产品)
- 别名
- ARS2 antibody, ASR2 antibody, serrate antibody, SERRATE antibody, T20P8.15 antibody, T20P8_15 antibody, serrate, RNA effector molecule antibody, C2H2 zinc-finger protein SERRATE (SE) antibody, SRRT antibody, SE antibody
- 背景
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Synonyms: serrate, RNA effector molecule , ARS2 , ASR2 , serrate
Background: Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation. Contributes to the stability and delivery of capped primary miRNA transcripts to the primary miRNA processing complex containing DGCR8 and RNASEN, thereby playing a role in RNA-mediated gene silencing (RNAi) by miRNAs. Binds capped RNAs (m7GpppG-capped RNA), however interaction is probably mediated via its interaction with NCBP1/CBP80 component of the CBC complex. Involved in cell cycle progression at S phase. Does not directly confer arsenite resistance but rather modulates arsenic sensitivity.
- 分子量
- 101 kDa
- 基因ID
- 51593
- UniProt
- Q9BXP5
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