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PPFIBP1 抗体

PPFIBP1 适用: 人 WB, IHC (p) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7468824
发货至: 中国
  • 抗原 See all PPFIBP1 抗体
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    适用
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    宿主
    • 31
    克隆类型
    • 31
    多克隆
    标记
    • 14
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    This PPFIBP1 antibody is un-conjugated
    应用范围
    • 24
    • 19
    • 2
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    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    交叉反应
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human PPFIBP1. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product PPFIBP1 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    PPFIBP1 (PTPRF Interacting Protein, Binding Protein 1 (Liprin beta 1) (PPFIBP1))
    别名
    PPFIA binding protein 1 (PPFIBP1 产品)
    别名
    liprin-beta-1 antibody, L2 antibody, SGT2 antibody, hSGT2 antibody, hSgt2p antibody, 4632409B19Rik antibody, AW214454 antibody, AW261454 antibody, PPFIA binding protein 1 antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) antibody, PTPRF interacting protein, binding protein 1 (liprin beta 1) S homeolog antibody, Ppfibp1 antibody, ppfibp1 antibody, ppfibp1.S antibody, PPFIBP1 antibody
    背景

    Synonyms: PPFIA binding protein 1 , L2 , SGT2 , hSGT2 , hSgt2p

    Background: The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein was found to interact with S100A4, a calcium-binding protein related to tumor invasiveness and metastasis. In vitro experiment demonstrated that the interaction inhibited the phosphorylation of this protein by protein kinase C and protein kinase CK2. Alternatively spliced transcript variants encoding distinct isoforms have been reported. [provided by RefSeq]

    分子量
    114 kDa
    基因ID
    8496
    UniProt
    Q86W92
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