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LIN7A 抗体

LIN7A 适用: 人 WB, IF, IP, ICC 宿主: 小鼠 Monoclonal GT879 unconjugated
产品编号 ABIN7468550
发货至: 中国
  • 抗原 See all LIN7A 抗体
    LIN7A (Lin-7 Homolog A (LIN7A))
    适用
    • 30
    • 6
    • 4
    • 1
    • 1
    宿主
    • 27
    • 3
    小鼠
    克隆类型
    • 29
    • 1
    单克隆
    标记
    • 16
    • 4
    • 3
    • 3
    • 2
    • 2
    This LIN7A antibody is un-conjugated
    应用范围
    • 26
    • 20
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    交叉反应
    纯化方法
    Affinity purified by Protein G.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human LIN7A. The exact sequence is proprietary.
    克隆位点
    GT879
    亚型
    IgG1
    Top Product
    Discover our top product LIN7A Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IP: 1:100-1:500. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: MCF-7 , MDA-MB-231

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    PBS, No Preservative
    储存液
    Without preservative
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    LIN7A (Lin-7 Homolog A (LIN7A))
    别名
    lin-7 homolog A, crumbs cell polarity complex component (LIN7A 产品)
    别名
    LIN-7A antibody, LIN7 antibody, MALS-1 antibody, TIP-33 antibody, VELI1 antibody, lin7b antibody, zgc:73090 antibody, AI848705 antibody, Veli antibody, Veli1 antibody, lin-7 homolog A, crumbs cell polarity complex component antibody, lin-7 homolog A (C. elegans) antibody, LIN7A antibody, lin7a antibody, Lin7a antibody
    背景

    Synonyms: lin-7 homolog A, crumbs cell polarity complex component , LIN-7A , LIN7 , MALS-1 , MALS1 , TIP-33 , VELI1

    Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.

    分子量
    26 kDa
    基因ID
    8825
    UniProt
    O14910
    途径
    Synaptic Membrane
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