LIN7A 抗体
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- 抗原 See all LIN7A 抗体
- LIN7A (Lin-7 Homolog A (LIN7A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This LIN7A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Whole Mount) (IHC (wm))
- 交叉反应
- 人, 小鼠, 斑马鱼
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human LIN7A. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product LIN7A Primary Antibody
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anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibody
LIN7A 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-233) antibodyLIN7A 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Lin-7 Homolog A (LIN7A) (AA 1-90) antibodyLIN7A 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:1000-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: MCF-7
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 1 % BSA, 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- LIN7A (Lin-7 Homolog A (LIN7A))
- 别名
- lin-7 homolog A, crumbs cell polarity complex component (LIN7A 产品)
- 别名
- LIN-7A antibody, LIN7 antibody, MALS-1 antibody, TIP-33 antibody, VELI1 antibody, lin7b antibody, zgc:73090 antibody, AI848705 antibody, Veli antibody, Veli1 antibody, lin-7 homolog A, crumbs cell polarity complex component antibody, lin-7 homolog A (C. elegans) antibody, LIN7A antibody, lin7a antibody, Lin7a antibody
- 背景
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Synonyms: lin-7 homolog A, crumbs cell polarity complex component , LIN-7A , LIN7 , MALS-1 , MALS1 , TIP-33 , VELI1
Background: Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells. Forms membrane-associated multiprotein complexes that may regulate delivery and recycling of proteins to the correct membrane domains. The tripartite complex composed of LIN7 (LIN7A, LIN7B or LIN7C), CASK and APBA1 may have the potential to couple synaptic vesicle exocytosis to cell adhesion in brain. Ensures the proper localization of GRIN2B (subunit 2B of the NMDA receptor) to neuronal postsynaptic density and may function in localizing synaptic vesicles at synapses where it is recruited by beta-catenin and cadherin. Required to localize Kir2 channels, GABA transporter (SLC6A12) and EGFR/ERBB1, ERBB2, ERBB3 and ERBB4 to the basolateral membrane of epithelial cells.
- 分子量
- 26 kDa
- 基因ID
- 8825
- UniProt
- O14910
- 途径
- Synaptic Membrane
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