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KDELR1 抗体

KDELR1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7468512
发货至: 中国
  • 抗原 See all KDELR1 抗体
    KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
    适用
    • 19
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    宿主
    • 18
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    克隆类型
    • 17
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    多克隆
    标记
    • 10
    • 2
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    This KDELR1 antibody is un-conjugated
    应用范围
    • 20
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    Western Blotting (WB)
    交叉反应
    Hamster
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human KDEL receptor. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product KDELR1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    0.729 mg/mL
    缓冲液
    0.1M Tris-Glycine ( pH 7), 10 % Glycerol, 0.01 % Thimerosal
    储存液
    Thimerosal (Merthiolate)
    注意事项
    This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    KDELR1 (KDEL (Lys-Asp-Glu-Leu) Endoplasmic Reticulum Protein Retention Receptor 1 (KDELR1))
    别名
    KDEL endoplasmic reticulum protein retention receptor 1 (KDELR1 产品)
    别名
    ERD2 antibody, ERD2.1 antibody, HDEL antibody, PM23 antibody, 8030486F04Rik antibody, AW215843 antibody, Erd2.1 antibody, KDEL endoplasmic reticulum protein retention receptor 1 antibody, KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1 antibody, KDELR1 antibody, Kdelr1 antibody
    背景

    Synonyms: KDEL endoplasmic reticulum protein retention receptor 1 , ERD2 , ERD2.1 , HDEL , PM23

    Background: Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq]

    分子量
    25 kDa
    基因ID
    10945
    UniProt
    P24390
    途径
    Maintenance of Protein Location
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