EIF5A 抗体
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- 抗原 See all EIF5A 抗体
- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This EIF5A antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人, 小鼠, 大鼠
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Full length human EIF5A Recombinant protein.
- 亚型
- IgG
- Top Product
- Discover our top product EIF5A Primary Antibody
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- 应用备注
- WB: 1:500-1:10000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: PC-12 , Rat2
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.4 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- EIF5A (Eukaryotic Translation Initiation Factor 5A (EIF5A))
- 别名
- eukaryotic translation initiation factor 5A (EIF5A 产品)
- 背景
- Eukaryotic translation initiation factor 5A , EIF-5A , EIF5A1 , eIF5AI,mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of TP53/p53 and TP53/p53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
- 分子量
- 17 kDa
- 基因ID
- 1984
- UniProt
- P63241
- 途径
- Regulation of Muscle Cell Differentiation
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