C14orf169 + NO66 抗体 (C-Term)
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- 抗原 See all C14orf169 + NO66 (C14orf169) 抗体
- C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C14orf169 + NO66 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the C-terminus region of human C14orf169 / NO66. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product C14orf169 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: NT2D1
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- C14orf169 + NO66 (C14orf169) (Chromosome 14 Open Reading Frame 169 (C14orf169))
- 别名
- ribosomal oxygenase 1 (C14orf169 产品)
- 别名
- LOC453015 antibody, C10H14orf169 antibody, MAPJD antibody, NO66 antibody, ROX antibody, C14orf169 antibody, No66 antibody, im:7141580 antibody, no66 antibody, chromosome 14 open reading frame 169 antibody, ribosomal oxygenase 1 antibody, chromosome 5 open reading frame, human C14orf169 antibody, LOC453015 antibody, Bm1_08415 antibody, RIOX1 antibody, C5H14ORF169 antibody, Riox1 antibody, riox1 antibody
- 背景
- Ribosomal oxygenase 1 , C14orf169 , JMJD9 , MAPJD , NO66 , ROX , URLC2 , hsNO66,Histone demethylase that specifically demethylates 'Lys-4' (H3K4me) and 'Lys-36' (H3K36me) of histone H3, thereby playing a central role in histone code. Preferentially demethylates trimethylated H3 'Lys-4' (H3K4me3) and monomethylated H3 'Lys-4' (H3K4me1) residues, while it has weaker activity for dimethylated H3 'Lys-36' (H3K36me2). Acts as a regulator of osteoblast differentiation via its interaction with SP7/OSX by demethylating H3K4me and H3K36me, thereby inhibiting SP7/OSX-mediated promoter activation (By similarity). May also play a role in ribosome biogenesis and in the replication or remodeling of certain heterochromatic region.
- 分子量
- 71 kDa
- 基因ID
- 79697
- UniProt
- Q9H6W3
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