CAPN10 抗体
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- 抗原 See all CAPN10 抗体
- CAPN10 (Calpain 10 (CAPN10))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CAPN10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human Calpain 10. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product CAPN10 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: HeLa
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.48 mg/mL
- 缓冲液
- 0.1M Tris-Glycine ( pH 7), 20 % Glycerol, 0.01 % Thimerosal
- 储存液
- Thimerosal (Merthiolate)
- 注意事项
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- CAPN10 (Calpain 10 (CAPN10))
- 别名
- calpain 10 (CAPN10 产品)
- 别名
- CAPN10 antibody, CANP10 antibody, NIDDM1 antibody, AW049679 antibody, Capn8 antibody, mKIAA1845 antibody, calpain 10 antibody, calpain 10 L homeolog antibody, CAPN10 antibody, capn10.L antibody, capn10 antibody, Capn10 antibody
- 背景
- Calpain 10 , CANP10 , NIDDM1,Calpains are ubiquitous, well-conserved family of calcium-dependent, cysteine proteases. The calpain proteins are heterodimers consisting of an invariant small subunit and variable large subunits. The large catalytic subunit has four domains: domain I, the N-terminal regulatory domain that is processed upon calpain activation, domain II, the protease domain, domain III, a linker domain of unknown function, and domain IV, the calmodulin-like calcium-binding domain. This gene encodes a large subunit. It is an atypical calpain in that it lacks the calmodulin-like calcium-binding domain and instead has a divergent C-terminal domain. It is similar in organization to calpains 5 and 6. This gene is associated with type 2 or non-insulin-dependent diabetes mellitus (NIDDM) and located within the NIDDM1 region. Multiple alternative transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq]
- 分子量
- 75 kDa
- 基因ID
- 11132
- UniProt
- Q9HC96
- 途径
- Positive Regulation of Peptide Hormone Secretion
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