USP20 抗体
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- 抗原 See all USP20 抗体
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP20 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Affinity purified by Protein A.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human USP20. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product USP20 Primary Antibody
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anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibody
USP20 适用: 人, 犬, 兔, 马, Hamster IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Internal Region) antibodyUSP20 适用: 人, 犬, 兔, 马, Pig, 小鸡, Cow, 猴, Bat IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 252-349) antibodyUSP20 适用: 人 ELISA, WB 宿主: 小鼠 Monoclonal 1A6 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 1-913) antibodyUSP20 适用: 人 WB 宿主: 小鼠 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (C-Term) antibodyVerified USP20 适用: 人 ELISA, WB, IHC 宿主: 山羊 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 361-410) antibodyUSP20 适用: 人, 大鼠, 兔, 小鸡, 猴, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (AA 814-844), (C-Term) antibodyUSP20 适用: 小鼠 WB, IHC (p) 宿主: 兔 Polyclonal RB4351 unconjugated
anti-Ubiquitin Specific Peptidase 20 (USP20) (Middle Region) antibodyUSP20 适用: 人, 小鼠, 犬, 大鼠, 兔, 马, Cow, 豚鼠 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , Raji
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 0.98 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
- 别名
- ubiquitin specific peptidase 20 (USP20 产品)
- 别名
- USP20 antibody, vdu2 antibody, lsfr3a antibody, LSFR3A antibody, VDU2 antibody, hVDU2 antibody, 1700055M05Rik antibody, AI467231 antibody, Vdu2 antibody, im:7151955 antibody, zgc:63661 antibody, universal stress protein antibody, ubiquitin specific peptidase 20 antibody, ubiquitin specific peptidase 20 L homeolog antibody, RR_RS15875 antibody, USP20 antibody, usp20 antibody, Usp20 antibody, usp20.L antibody
- 背景
- Ubiquitin specific peptidase 20 , LSFR3A , VDU2 , hVDU2,Deubiquitinating enzyme involved in beta-2 adrenergic receptor (ADRB2) recycling. Acts as a regulator of G-protein coupled receptor (GPCR) signaling by mediating the deubiquitination beta-2 adrenergic receptor (ADRB2). Plays a central role in ADRB2 recycling and resensitization after prolonged agonist stimulation by constitutively binding ADRB2, mediating deubiquitination of ADRB2 and inhibiting lysosomal trafficking of ADRB2. Upon dissociation, it is probably transferred to the translocated beta-arrestins, possibly leading to beta-arrestins deubiquitination and disengagement from ADRB2. This suggests the existence of a dynamic exchange between the ADRB2 and beta-arrestins. Deubiquitinates DIO2, thereby regulating thyroid hormone regulation. Deubiquitinates HIF1A, leading to stabilize HIF1A and enhance HIF1A-mediated activity. Mediates deubiquitination of both 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
- 分子量
- 102 kDa
- 基因ID
- 10868
- UniProt
- Q9Y2K6
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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