HERC5 抗体
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- 抗原 See all HERC5 抗体
- HERC5 (Hect Domain and RLD 5 (HERC5))
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This HERC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB)
- 交叉反应
- 人
- 纯化方法
- Purified by antigen-affinity chromatography.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human HERC5. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product HERC5 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T
Validation: KO/KD
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 3.96 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- HERC5 (Hect Domain and RLD 5 (HERC5))
- 别名
- HECT and RLD domain containing E3 ubiquitin protein ligase 5 (HERC5 产品)
- 别名
- HERC5 antibody, CEB1 antibody, CEBP1 antibody, HECT and RLD domain containing E3 ubiquitin protein ligase 5 antibody, hect domain and RLD 5 antibody, HERC5 antibody
- 背景
- HECT and RLD domain containing E3 ubiquitin protein ligase 5 , CEB1 , CEBP1,This gene is a member of the HERC family of ubiquitin ligases and encodes a protein with a HECT domain and five RCC1 repeats. Pro-inflammatory cytokines upregulate expression of this gene in endothelial cells. The protein localizes to the cytoplasm and perinuclear region and functions as an interferon-induced E3 protein ligase that mediates ISGylation of protein targets. The gene lies in a cluster of HERC family genes on chromosome 4. [provided by RefSeq]
- 分子量
- 117 kDa
- 基因ID
- 51191
- UniProt
- Q9UII4
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