TET1 抗体
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- 抗原 See all TET1 抗体
- TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
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适用
- 人
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宿主
- 小鼠
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克隆类型
- 单克隆
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标记
- This TET1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Affinity purified by Protein G.
- 质量等级
- KO Validated
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human TET1. The exact sequence is proprietary.
- 克隆位点
- GT1462
- 亚型
- IgG2b
- Top Product
- Discover our top product TET1 Primary Antibody
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- 应用备注
- WB: 1:500-1:3000. ICC/IF: 1:100-1:1000. IHC-P: 1:100-1:1000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
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Positive Control: 293T , DDDDK-human TET1-transfected 293T cells , NT2D1 nuclear extract
Validation: KO/KD, Orthogonal, Overexpression
- 限制
- 仅限研究用
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- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- PBS, No Preservative
- 储存液
- Without preservative
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- 抗原
- TET1 (Tet Methylcytosine Dioxygenase 1 (TET1))
- 别名
- tet methylcytosine dioxygenase 1 (TET1 产品)
- 别名
- CXXC6 antibody, LCX antibody, bA119F7.1 antibody, 2510010B09Rik antibody, AA517754 antibody, BB001228 antibody, Cxxc6 antibody, D10Ertd17e antibody, mKIAA1676 antibody, tet methylcytosine dioxygenase 1 antibody, solute carrier family 25 member 16 antibody, TET1 antibody, Tet1 antibody, SLC25A16 antibody
- 背景
- Tet methylcytosine dioxygenase 1 , CXXC6 , LCX , bA119F7.1,Dioxygenase that specifically binds methylcytosine (5mC), a minor base in mammalian DNA found in repetitive DNA elements that is crucial for retrotransposon silencing and mammalian development. Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). The clear function of 5-hydroxymethylcytosine (hmC) is still unclear but it may influence chromatin structure and recruit specific factors or may constitute an intermediate component in cytosine demethylation. 5-hydroxymethylcytosine (hmC) is present in ES cells and is enriched in the brain, especially in Purkinje neurons. May play a role in the fetal development of heart, lung and brain.
- 分子量
- 235 kDa
- 基因ID
- 80312
- UniProt
- Q8NFU7
- 途径
- Stem Cell Maintenance, Warburg Effect
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