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MED13 抗体

MED13 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7464200
发货至: 中国
  • 抗原 See all MED13 抗体
    MED13 (Mediator Complex Subunit 13 (MED13))
    适用
    • 18
    • 4
    • 1
    宿主
    • 18
    克隆类型
    • 18
    多克隆
    标记
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MED13 antibody is un-conjugated
    应用范围
    • 8
    • 7
    • 3
    • 3
    • 2
    Western Blotting (WB)
    特异性
    Knockdown/Knockout validation was supported by references (PMID:36220895)
    交叉反应
    人, 小鼠
    纯化方法
    Purified by antigen-affinity chromatography.
    免疫原
    Recombinant protein encompassing a sequence within the center region of human MED13. The exact sequence is proprietary.
    亚型
    IgG
    Top Product
    Discover our top product MED13 Primary Antibody
  • 应用备注
    WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
    说明

    Positive Control: 293T , A431 , HeLa , HepG2

    Validation: Orthogonal

    限制
    仅限研究用
  • 状态
    Liquid
    浓度
    1 mg/mL
    缓冲液
    1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C,-20 °C
    储存方法
    Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
  • 抗原
    MED13 (Mediator Complex Subunit 13 (MED13))
    别名
    mediator complex subunit 13 (MED13 产品)
    别名
    ARC250 antibody, DRIP250 antibody, HSPC221 antibody, THRAP1 antibody, TRAP240 antibody, 1110067M05Rik antibody, D030023K18 antibody, Thrap1 antibody, Trap240 antibody, med13 antibody, wu:fb66c06 antibody, wu:fc43h07 antibody, wu:fc43h08 antibody, zgc:153454 antibody, skuld-like antibody, mediator complex subunit 13 antibody, mediator complex subunit 13b antibody, MED13 antibody, Med13 antibody, med13b antibody
    背景
    Mediator complex subunit 13 , ARC250 , DRIP250 , HSPC221 , THRAP1 , TRAP240,This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq]
    分子量
    239 kDa
    基因ID
    9969
    UniProt
    Q9UHV7
    途径
    Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
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