MED13 抗体
-
- 抗原 See all MED13 抗体
- MED13 (Mediator Complex Subunit 13 (MED13))
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This MED13 antibody is un-conjugated
-
应用范围
- Western Blotting (WB)
- 特异性
- Knockdown/Knockout validation was supported by references (PMID:36220895)
- 交叉反应
- 人, 小鼠
- 纯化方法
- Purified by antigen-affinity chromatography.
- 免疫原
- Recombinant protein encompassing a sequence within the center region of human MED13. The exact sequence is proprietary.
- 亚型
- IgG
- Top Product
- Discover our top product MED13 Primary Antibody
-
-
- 应用备注
- WB: 1:500-1:3000. Optimal dilutions/concentrations should be determined by the researcher. Not tested in other applications.
- 说明
-
Positive Control: 293T , A431 , HeLa , HepG2
Validation: Orthogonal
- 限制
- 仅限研究用
-
- 状态
- Liquid
- 浓度
- 1 mg/mL
- 缓冲液
- 1XPBS ( pH 7), 20 % Glycerol, 0.025 % ProClin 300
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C,-20 °C
- 储存方法
- Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4°C. For long-term storage, aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
-
- 抗原
- MED13 (Mediator Complex Subunit 13 (MED13))
- 别名
- mediator complex subunit 13 (MED13 产品)
- 别名
- ARC250 antibody, DRIP250 antibody, HSPC221 antibody, THRAP1 antibody, TRAP240 antibody, 1110067M05Rik antibody, D030023K18 antibody, Thrap1 antibody, Trap240 antibody, med13 antibody, wu:fb66c06 antibody, wu:fc43h07 antibody, wu:fc43h08 antibody, zgc:153454 antibody, skuld-like antibody, mediator complex subunit 13 antibody, mediator complex subunit 13b antibody, MED13 antibody, Med13 antibody, med13b antibody
- 背景
- Mediator complex subunit 13 , ARC250 , DRIP250 , HSPC221 , THRAP1 , TRAP240,This gene encodes a component of the mediator complex (also known as TRAP, SMCC, DRIP, or ARC), a transcriptional coactivator complex thought to be required for the expression of almost all genes. The mediator complex is recruited by transcriptional activators or nuclear receptors to induce gene expression, possibly by interacting with RNA polymerase II and promoting the formation of a transcriptional pre-initiation complex. The product of this gene is proposed to form a sub-complex with MED12, cyclin C, and CDK8 that can negatively regulate transactivation by mediator. [provided by RefSeq]
- 分子量
- 239 kDa
- 基因ID
- 9969
- UniProt
- Q9UHV7
- 途径
- Intracellular Steroid Hormone Receptor Signaling Pathway, Nuclear Hormone Receptor Binding, Regulation of Lipid Metabolism by PPARalpha
-