SELPLG 抗体 (FITC)
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- 抗原 See all SELPLG 抗体
- SELPLG (Selectin P Ligand (SELPLG))
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适用
- 小鼠
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宿主
- 大鼠
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克隆类型
- 单克隆
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标记
- This SELPLG antibody is conjugated to FITC
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应用范围
- Flow Cytometry (FACS)
- 克隆位点
- 4RA10
- 亚型
- IgG1, kappa
- Top Product
- Discover our top product SELPLG Primary Antibody
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- 应用备注
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
- 说明
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Matching Isotype Control: FITC Rat IgG1, κ Isotype Control (ABIN7469821)
- 限制
- 仅限研究用
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- 浓度
- 0.5 mg/mL
- 缓冲液
- PBS with 0.05 % Proclin300, 1 % BSA
- 储存液
- ProClin
- 注意事项
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 储存方法
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- 抗原
- SELPLG (Selectin P Ligand (SELPLG))
- 别名
- CD162 (SELPLG 产品)
- 别名
- CD162 antibody, CLA antibody, PSGL-1 antibody, PSGL1 antibody, SELPLG antibody, SELPG antibody, Psgl-1 antibody, Psgl1 antibody, Selp1 antibody, Selpl antibody, selectin P ligand antibody, selectin, platelet (p-selectin) ligand antibody, clasper antibody, SELPLG antibody, Selplg antibody, cla antibody
- 背景
- P-selectin glycoprotein ligand 1,Selplg,PSGL-1,Selectin P ligand,CD162,The 4RA10 antibody reacts with the N-terminal functional peptide of CD162 (P-selectin glycoprotein ligand-1, PSGL-1), encoded by the Selpl gene. PSGL-1 is expressed on the cell surface as a homodimer of approximately 230 kDa. In the mouse, Selpl mRNA is detected in most tissues, with high levels found in hematopoietic cells, brain, and adipose tissue. Flow cytometric analyses have revealed CD162 expression on bone marrow-derived mast and dendritic cells, splenic leukocytes, platelets, peripheral blood neutrophils, and neutrophil and T-cell lines. PSGL-1 is a ligand for P-selectin (CD62P) and is involved in leukocyte rolling, the migration of leukocytes into inflamed tissues, and responses to vascular injury. It is a sialomucin that must be specifically sialylated, fucosylated, and sulfated to bind P-selectin. There is also evidence that other ligands for PSGL-1 and CD62P may exist. 4RA10 mAb is reported to block the binding of mouse leukocytes to CD62P and CD62L.
- 基因ID
- 20345
- UniProt
- Q62170
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