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CCR6 抗体 (APC)

CCR6 适用: 人 FACS 宿主: 小鼠 Monoclonal G034E3 APC
产品编号 ABIN7456504
发货至: 中国
  • 抗原 See all CCR6 抗体
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    适用
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    宿主
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    小鼠
    克隆类型
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    单克隆
    标记
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    This CCR6 antibody is conjugated to APC
    应用范围
    • 26
    • 21
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    • 1
    Flow Cytometry (FACS)
    克隆位点
    G034E3
    亚型
    IgG2b, kappa
    Top Product
    Discover our top product CCR6 Primary Antibody
  • 应用备注
    The amount of the reagent is suggested to be used 5 µL of antibody per test (million cells in 100 µL staining volume or per 100 µL of whole blood). Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.
    说明

    Matching Isotype Control: APC Mouse IgG2b, κ Isotype Control (ABIN7469796)

    限制
    仅限研究用
  • 缓冲液
    PBS with 0.05 % Proclin300, 1 % BSA
    储存液
    ProClin
    注意事项
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    储存方法
    Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
  • 抗原
    CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))
    别名
    CD196/CCR6 (CCR6 产品)
    别名
    BN-1 antibody, C-C CKR-6 antibody, CC-CKR-6 antibody, CCR-6 antibody, CD196 antibody, CKR-L3 antibody, CKRL3 antibody, CMKBR6 antibody, DCR2 antibody, DRY6 antibody, GPR29 antibody, GPRCY4 antibody, STRL22 antibody, Cmkbr6 antibody, KY411 antibody, C-C motif chemokine receptor 6 antibody, chemokine (C-C motif) receptor 6 antibody, CCR6 antibody, Ccr6 antibody
    背景
    CKRL3, CMKBR6, GPR29, STRL22,GPRCY4,CCR6, also known as CD196/CCR6, is a chemokine receptor that is expressed on immature dendritic cells, B lymphocytes, and memory T cells. CCR6 binds CCL20, although members of the β defensin family also bind CCR6 with a lower affinity. CCR6 positive cells, and its ligand CCL20, have been detected in numerous organs, especially the secondary lymphoid organ. CCL20 is selectively made by the follicle-associated epithelium (FAE) overlying Peyers Patches (PPs) and isolated lymphoid follicles (ILFs). CCL20 contributes to the recruitment of CCR6-expressing B cells to these structures. In humans, CCR6 can function to mediate arrest of T cells on dermal endothelial cells and is highly expressed on T cells resident in both normal and psoriatic skin. CCR6 and/or CCL20 have been implicated in the pathogenesis of rheumatoid arthritis and inflammatory bowel disease. Human T cells that are able to produce IL-17 express CCR6. It suggests that CCL20 and CCR6 have a role in inflammatory diseases by recruiting Th17 cells to target tissues.
    基因ID
    1235
    UniProt
    P51684
    途径
    cAMP Metabolic Process
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