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SIGLEC7 抗体

SIGLEC7 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
产品编号 ABIN7490814
发货至: 中国
  • 抗原 See all SIGLEC7 抗体
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    片段
    Fc fragment
    适用
    • 83
    • 11
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    宿主
    • 62
    • 21
    克隆类型
    • 63
    • 20
    Chimeric
    标记
    • 37
    • 12
    • 10
    • 7
    • 6
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SIGLEC7 antibody is un-conjugated
    应用范围
    • 61
    • 44
    • 40
    • 15
    • 9
    • 6
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    产品特性
    Rabbit/Human Fc chimeric IgG1
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product SIGLEC7 Primary Antibody
  • 应用备注
    Flow Cyt 1:100
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    SIGLEC7 (Sialic Acid Binding Ig-Like Lectin 7 (SIGLEC7))
    别名
    SIGLEC7 (SIGLEC7 产品)
    别名
    SIGLEC7 antibody, AIRM1 antibody, CD328 antibody, CDw328 antibody, D-siglec antibody, QA79 antibody, SIGLEC-7 antibody, SIGLEC19P antibody, SIGLECP2 antibody, p75 antibody, p75/AIRM1 antibody, sialic acid-binding Ig-like lectin 7 antibody, sialic acid binding Ig like lectin 7 antibody, LOC468976 antibody, SIGLEC7 antibody
    背景
    AIRM-1, AIRM1, CD328, CDw328, D-siglec, p75, p75/AIRM1, QA79, SIGLEC-7, SIGLEC19P, SIGLECP2,
    Description: Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,3- and alpha-2,6-linked sialic acid. Also binds disialogangliosides (disialogalactosyl globoside, disialyl lactotetraosylceramide and disialyl GalNAc lactotetraoslylceramide). The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Mediates inhibition of natural killer cells cytotoxicity. May play a role in hemopoiesis. Inhibits differentiation of CD34 cell precursors towards myelomonocytic cell lineage and proliferation of leukemic myeloid cells (in vitro).[UniProtKB/Swiss-Prot Function]
    UniProt
    Q9Y286
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