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FLT3LG 抗体

FLT3LG 适用: 人 FACS 宿主: 兔 Chimeric unconjugated Fc fragment
产品编号 ABIN7490670
发货至: 中国
  • 抗原 See all FLT3LG 抗体
    FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
    片段
    Fc fragment
    适用
    • 59
    • 18
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    宿主
    • 52
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    克隆类型
    • 55
    • 7
    Chimeric
    标记
    • 31
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    This FLT3LG antibody is un-conjugated
    应用范围
    • 51
    • 25
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    • 9
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    Flow Cytometry (FACS)
    产品特性
    Rabbit/Human Fc chimeric IgG1
    纯化方法
    Purified from cell culture supernatant by affinity chromatography
    亚型
    IgG1
    Top Product
    Discover our top product FLT3LG Primary Antibody
  • 应用备注
    Flow Cyt  1:100
    限制
    仅限研究用
  • 状态
    Liquid
    储存条件
    -20 °C,-80 °C
    储存方法
    Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing). Lyophilized proteins are shipped at ambient temperature.
    有效期
    12 months
  • 抗原
    FLT3LG (Fms-Related tyrosine Kinase 3 Ligand (FLT3LG))
    别名
    FLT3LG (FLT3LG 产品)
    别名
    Flt3lg antibody, Ly72L antibody, FL antibody, FLT3L antibody, Vegfr3 antibody, fms related tyrosine kinase 3 ligand antibody, FMS-like tyrosine kinase 3 ligand antibody, fms-related tyrosine kinase 4 antibody, fms-related tyrosine kinase 3 ligand antibody, FLT3LG antibody, Flt3l antibody, Flt4 antibody, Flt3lg antibody
    背景
    FLT3LG, FL, FLT3L, Flt3 ligand
    Description: ,FMS-like tyrosine kinase 3 ligand (Flt-3 Ligand) is also known as FL, Flt3L and FLT3LG, is an α-helical cytokine that promotes the differentiation of multiple hematopoietic cell lineages. FLT3LG is expressed as a noncovalentlylinked dimer by T cells and bone marrow and thymic fibroblasts. Each 36 kDa chain carries approximately 12 kDa of N- and O- linked carbohydrates. FLT3LG is structurally homologous to stem cell factor (SCF) and colony stimulating facor 1 (CSF-1). FLT3LG acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. It also induces the mobilization of the hematopoietic progenitors and stem cells in vivo which may help the system to kill cancer cells. FLT3LG induces the expansion of monocytes and immature dendritic cells as well as early B cell lineage differentiation. FLT3LG cooperates with IL2, IL6, IL7, and IL15 to induce NK cell development and with IL3, IL7 and IL11 to induce terminal B cell maturation. Animal studies also show FLT3LG to reduce the severity of experimentally induced allergic inflammation. FLT3LG is crucial for steady-state pDC and cDC development. A lack of FLT3L results in low levels of DCs.
    UniProt
    P49771
    途径
    RTK signaling
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