Recombinant UBQLN4 抗体 (AA 2-601)
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- 抗原 See all UBQLN4 抗体
- UBQLN4 (Ubiquilin 4 (UBQLN4))
- 抗体类型
- Recombinant Antibody
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抗原表位
- AA 2-601
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适用
- 人
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宿主
- 兔
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克隆类型
- 单克隆
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标记
- This UBQLN4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunocytochemistry (ICC), Flow Cytometry (FACS), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Recombinant Monoclonal Antibody [BLR145J]
- 免疫原
- residues 2-601 (full length)
- 克隆位点
- BLR145J
- 亚型
- IgG
- Top Product
- Discover our top product UBQLN4 Primary Antibody
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anti-Ubiquilin 4 (UBQLN4) (AA 300-390) antibody
UBQLN4 适用: 人 WB, IHC, IF 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 287-336) antibodyUBQLN4 适用: 人, 小鼠, 大鼠, 兔, Cow, 马, 犬, Pig, 猴, 小鸡, 非洲爪蟾 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (Middle Region) antibodyUBQLN4 适用: 人, 小鼠, 大鼠, 兔, Cow, 马, 斑马鱼, 豚鼠, 犬, Pig, 绵羊 WB 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (AA 201-250) antibodyUBQLN4 适用: 人, 小鼠 WB, IHC, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Ubiquilin 4 (UBQLN4) (N-Term) antibodyUBQLN4 适用: 人, 小鼠, 大鼠 WB, IHC (p), EIA 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 20 μL/1 mg lysate
ICC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE cell sections.
WB: 01:01,00
- 限制
- 仅限研究用
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- 浓度
- 50 μg/mL
- 缓冲液
- Borate Buffered Saline (BBS) pH 8.2 with 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- UBQLN4 (Ubiquilin 4 (UBQLN4))
- 别名
- UBQLN4/CIP75/Ubiquilin 4 (UBQLN4 产品)
- 别名
- a1u antibody, cip75 antibody, ubin antibody, ubiquilin-4 antibody, A1U antibody, A1Up antibody, C1orf6 antibody, CIP75 antibody, UBIN antibody, A1u antibody, AI663987 antibody, RGD1308273 antibody, ubiquilin 4 L homeolog antibody, ubiquilin 4 antibody, ubqln4.L antibody, ubqln4 antibody, UBQLN4 antibody, Ubqln4 antibody
- 背景
- Background: Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
- 基因ID
- 56893
- NCBI登录号
- NP_064516
- UniProt
- Q9NRR5
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