PSMC4 抗体 (AA 368-418)
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- 抗原 See all PSMC4 抗体
- PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
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抗原表位
- AA 368-418
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PSMC4 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-PSMC4 Antibody, Affinity Purified
- 预测反应
- Mouse,Rat,Bovine
- 纯化方法
- Affinity Purified
- 免疫原
- Between AA 368 and 418
- 亚型
- IgG
- Top Product
- Discover our top product PSMC4 Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:1,000 - 1:5,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- PSMC4 (Proteasome (Prosome, Macropain) 26S Subunit, ATPase, 4 (PSMC4))
- 别名
- PSMC4 (PSMC4 产品)
- 别名
- NCU02260.1 antibody, AO090003000692 antibody, DDBDRAFT_0188209 antibody, DDBDRAFT_0191435 antibody, DDB_0188209 antibody, DDB_0191435 antibody, MIP224 antibody, RPT3 antibody, S6 antibody, TBP-7 antibody, TBP7 antibody, CIP21 antibody, Tbp7 antibody, 26S protease regulatory subunit 6B antibody, regulatory particle, ATPase-like-3 antibody, 26S proteasome regulatory subunit 6B antibody, proteasome 26S subunit, ATPase 4 antibody, proteasome (prosome, macropain) 26S subunit, ATPase, 4 antibody, LOC732870 antibody, rpt-3 antibody, ATEG_04674 antibody, LELG_01296 antibody, HCAG_00039 antibody, LOC5568998 antibody, GL50803_7950 antibody, EDI_044950 antibody, AOR_1_1218154 antibody, PTRG_03339 antibody, psmC4 antibody, prs6b antibody, LOC100381342 antibody, psmc4 antibody, PSMC4 antibody, Psmc4 antibody
- 背景
- Background: PSMC4 [proteasome (prosome, macropain) 26S subunit, ATPase, 4] is a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. PSMC4 interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1 [taken from NCBI Entrez Gene (Gene ID: 5704)].
- 基因ID
- 5704
- NCBI登录号
- NP_006494
- UniProt
- P43686
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
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