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PUS1 抗体 (AA 377-427)

PUS1 适用: 人 WB, IP, IHC (fp) 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7454768
发货至: 中国
  • 抗原 See all PUS1 抗体
    PUS1 (Pseudouridylate Synthase 1 (PUS1))
    抗原表位
    • 10
    • 8
    • 7
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 377-427
    适用
    • 31
    • 7
    • 7
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 31
    • 3
    克隆类型
    • 32
    • 2
    多克隆
    标记
    • 24
    • 2
    • 2
    • 2
    • 2
    • 2
    This PUS1 antibody is un-conjugated
    应用范围
    • 33
    • 17
    • 16
    • 5
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
    原理
    Rabbit anti-PUS1 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 377 and 427
    亚型
    IgG
    Top Product
    Discover our top product PUS1 Primary Antibody
  • 应用备注

    IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    PUS1 (Pseudouridylate Synthase 1 (PUS1))
    别名
    PUS1 (PUS1 产品)
    别名
    PUS1 antibody, A730013B20Rik antibody, MPUS1 antibody, mPus1p antibody, MLASA1 antibody, pseudouridylate synthase 1 antibody, pseudouridylate synthase 1, putative antibody, pseudouridine synthase 1 antibody, PUS1 antibody, PVX_093530 antibody, PKH_011400 antibody, Pus1 antibody
    背景
    Background: Pus1 (pseudouridylate synthase 1) is an enzyme that converts uridine to pseudouridine in non-coding RNA substrates. Pus1 modifies uridines at specific positions in a subset of tRNAs. Pseudouridylation is known to affect the structure of tRNAs and stabilize base-stacking and base-pairing in the anticodon loop. Pus1 activity is important for proper folding and function of tRNAs. Pus1 has also been shown to pseudouridylate SRA (steroid receptor RNA activator) and function as a coactivator. Defects in pseudouridylation are associated with the human disease, MLASA (myopathy with lactic acidosis and sideroblastic anemia), an autosomal recessive oxidative phosphorylataion disorder specific to skeletal muscle and bone marrow.
    基因ID
    80324
    NCBI登录号
    NP_079491
    UniProt
    Q9Y606
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