CENPF 抗体 (AA 2350-2400)
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- 抗原 See all CENPF 抗体
- CENPF (Centromere Protein F (CENPF))
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抗原表位
- AA 2350-2400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CENPF antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-CENP-F/Mitosin Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 2350 and 2400
- 亚型
- IgG
- Top Product
- Discover our top product CENPF Primary Antibody
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- 应用备注
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IHC: 1:200 - 1:1,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- CENPF (Centromere Protein F (CENPF))
- 别名
- CENP-F/Mitosin (CENPF 产品)
- 别名
- LOC100222985 antibody, 6530404A22Rik antibody, AI325968 antibody, CENF antibody, Lek1 antibody, PRO1779 antibody, mitosin antibody, im:7140452 antibody, im:7144238 antibody, im:7154719 antibody, im:7156761 antibody, si:ch211-152h14.2 antibody, hcp-1 antibody, CMF1 antibody, centromere protein F antibody, CENPF antibody, Cenpf antibody, cenpf antibody
- 背景
- Background: Centromere protein F (CENP-F) is a microtubule binding protein and component of the kinetochore. It is essential for kinetochore attachment, chromosome alignment, and the spindle checkpoint. CENP-F appears to be important to the association of the NudE-related proteins Ndel1 and Nde1 to the Lis1/dynein motor complex and their role in kinetochore function. CENP-F is a farnesylated protein and the farnesylation of CENP-F appears to be central to its role in mediating kinetochore-microtubule interactions as well as its degradation after mitosis. Recently, CENP-F expression has been correlated with markers of poor outcome in breast cancer.
- 基因ID
- 1063
- UniProt
- P49454
- 途径
- Chromatin Binding, M Phase, SARS-CoV-2 Protein Interactome, The Global Phosphorylation Landscape of SARS-CoV-2 Infection
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