PALB2 抗体 (AA 675-725)
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- 抗原 See all PALB2 抗体
- PALB2 (Partner and Localizer of BRCA2 (PALB2))
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抗原表位
- AA 675-725
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PALB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-PALB2 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 675 and 725
- 亚型
- IgG
- Top Product
- Discover our top product PALB2 Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- PALB2 (Partner and Localizer of BRCA2 (PALB2))
- 别名
- PALB2 (PALB2 产品)
- 别名
- PALB2 antibody, Fancn antibody, si:ch211-14k19.9 antibody, FANCN antibody, PNCA3 antibody, 4732427B05 antibody, BC066140 antibody, RGD1304759 antibody, partner and localizer of BRCA2 antibody, partner and localizer of BRCA2 L homeolog antibody, PALB2 antibody, palb2 antibody, palb2.L antibody, Palb2 antibody
- 背景
- Background: PALB2 (partner and localizer of BRCA2) interacts with BRCA2 and promotes BRCA2 localization and stability. PALB2 is also known as FANCN. Bi-allelic mutations in PALB2 result in Fanconi anemia disorder and breast cancer susceptibility. At the cellular level, PALB2 is important to the DNA damage response and chromosome stability and is essential to BRCA2 function.
- 基因ID
- 79728
- NCBI登录号
- NP_078951
- UniProt
- Q86YC2
- 途径
- DNA Damage Repair
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