PARP10 抗体 (AA 300-350)
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- 抗原 See all PARP10 抗体
- PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))
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抗原表位
- AA 300-350
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PARP10 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-PARP10 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 300 and 350
- 亚型
- IgG
- Top Product
- Discover our top product PARP10 Primary Antibody
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- 应用备注
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IHC: 1:500 to 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000: 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- PARP10 (Poly (ADP-Ribose) Polymerase Family, Member 10 (PARP10))
- 别名
- PARP10 (PARP10 产品)
- 别名
- ARTD10 antibody, PARP10 antibody, poly(ADP-ribose) polymerase family member 10 antibody, poly (ADP-ribose) polymerase family, member 10 antibody, PARP10 antibody, Parp10 antibody
- 背景
- Background: PARP10 is a member of the poly(ADP-ribose) polymerase (PARP) family involved in a variety of processes which includes DNA metabolism, the DNA damage response, transcription and the maintenance of genomic stability. Although each member of the PARP family exhibits poly(ADP-ribose) polymerase activity which catalyzes the attachment of ADP-ribose units from NAD+ to substrate proteins, the endogenous substrates of many of the family members, including PARP10, remain to be identified. Recent studies have shown that PARP10 is localized to the nucleoli and associates with RNA polymerase II. PARP10 is a substrate of and is activated by CDK2 and may serve an important function in cell proliferation.
- 基因ID
- 84875
- NCBI登录号
- NP_116178
- UniProt
- Q53GL7
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