OSR1 抗体 (AA 325-375)
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- 抗原 See all OSR1 抗体
- OSR1 (Odd-Skipped Related 1 (OSR1))
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抗原表位
- AA 325-375
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This OSR1 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-OSR1 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 325 and 375
- 亚型
- IgG
- Top Product
- Discover our top product OSR1 Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-OSR1 antibody A301-579A.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- OSR1 (Odd-Skipped Related 1 (OSR1))
- 别名
- OSR1 (OSR1 产品)
- 别名
- XOsr1 antibody, odd antibody, odd1 antibody, znf91 antibody, ODD antibody, Odd1 antibody, Osr antibody, OXSR1 antibody, zgc:101674 antibody, odd-skipped related transciption factor 1 antibody, odd-skipped related 1 (Drosophila) antibody, OSR1 antibody, osr1 antibody, Osr1 antibody
- 背景
- Background: Oxidative stress responsive 1 (OSR1) is a STE20-related kinase involved in ion transport and fluid and ion homeostasis. OSR1 interacts with SPAK (STE20/SPS1-reated proline/alanine-rich kinase) and together are activated by the upstream kinase WNK1 [with no K (lysine) protein kinase-1]. Activation of OSR1 and SPAK by WNK1 results in the phosphorylation and activation of NKCC1 (Na+-K+-2Cl- co-transporter 1) for the control of cell volume and blood pressure.
- 基因ID
- 9943
- NCBI登录号
- NP_005100
- UniProt
- O95747
- 途径
- Tube Formation
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