CDC20 抗体 (AA 50-100)
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- 抗原 See all CDC20 抗体
- CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
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抗原表位
- AA 50-100
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CDC20 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-CDC20 Antibody, Affinity Purified
- 预测反应
- Pig
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 50 and 100
- 亚型
- IgG
- Top Product
- Discover our top product CDC20 Primary Antibody
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- 应用备注
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IHC: 1:200 - 1:1,000. Epitope retrieval with Tris-EDTA pH 9.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-CDC20 antibody A301-180A.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- CDC20 (Cell Division Cycle 20 Homolog (S. Cerevisiae) (CDC20))
- 别名
- CDC20 (CDC20 产品)
- 别名
- X-FZY antibody, ba276h19.3 antibody, cdc20a antibody, fizzy1 antibody, p55cdc antibody, CDC20A antibody, bA276H19.3 antibody, p55CDC antibody, 2310042N09Rik antibody, C87100 antibody, cell division cycle 20 antibody, cell division cycle 20 L homeolog antibody, cell division cycle 20 homolog (S. cerevisiae) antibody, cdc20 antibody, CDC20 antibody, cdc20.L antibody, Cdc20 antibody
- 背景
- Background: CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.
- 基因ID
- 991
- NCBI登录号
- NP_001246
- UniProt
- Q12834
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