PELP1 抗体 (AA 25-75)
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- 抗原 See all PELP1 抗体
- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
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抗原表位
- AA 25-75
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This PELP1 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-PELP1/MNAR Antibody, Affinity Purified
- 预测反应
- Monkey
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 25 and 75
- 亚型
- IgG
- Top Product
- Discover our top product PELP1 Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-PELP1/MNAR antibody A300-180A.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- PELP1 (Proline-, Glutamic Acid- and Leucine-Rich Protein 1 (PELP1))
- 别名
- PELP1/MNAR (PELP1 产品)
- 别名
- MNAR antibody, P160 antibody, RGD1306320 antibody, 4930563C04Rik antibody, proline, glutamate and leucine rich protein 1 antibody, proline, glutamate and leucine rich protein 1 L homeolog antibody, proline, glutamic acid and leucine rich protein 1 antibody, PELP1 antibody, Pelp1 antibody, pelp1.L antibody
- 背景
- Background: PELP1/MNAR was identified as an SH2 domain interacting protein that interacts with Lck, c-Src, and other members of the Src kinase family. PELP1/MNAR appears to function as a general coregulator and interacts with multiple nuclear receptors and transcription factors. PELP1/MNAR has also been shown to participate in nongenomic signaling via an association with a multiprotein complex, the ""signalsome"" involving ERalpha, Src kinase, PI3K, SHC, and G-proteins. As a transcriptional coregulator and signaling protein, PELP/MNAR mediates a variety of cellular functions such as cell proliferation, apoptosis, differentiation, oncogenesis and metastasis.
- 基因ID
- 27043
- UniProt
- Q8IZL8
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