KDM4A 抗体 (AA 350-400)
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- 抗原 See all KDM4A 抗体
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
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抗原表位
- AA 350-400
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This KDM4A antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-JMJD2A Antibody, Affinity Purified
- 预测反应
- Orangutan
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 350 and 400
- 亚型
- IgG
- Top Product
- Discover our top product KDM4A Primary Antibody
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- 应用备注
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IHC: 1:500 - 1:2,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-JMJD2A antibody A300-861A.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- KDM4A (Lysine (K)-Specific Demethylase 4A (KDM4A))
- 别名
- JMJD2A (KDM4A 产品)
- 别名
- JMJD2A antibody, JHDM3A antibody, JMJD2 antibody, TDRD14A antibody, D4Ertd222e antibody, Jmjd2 antibody, Jmjd2a antibody, mKIAA0677 antibody, lysine demethylase 4A antibody, lysine-specific demethylase 4A antibody, lysine (K)-specific demethylase 4A antibody, KDM4A antibody, LOC100228023 antibody, Kdm4a antibody
- 背景
- Background: JMJD2A is a member of the jumonji (jmj) domain containing gene family of histone demethylases that plays a role in chromatin regulation and influences transcriptional activation and suppression. Some recently characterized members of the jmj family include JARID1A/RBP2, JARID1C, JMJD1A, JMJD1B, JMJD1C, JMJD2A, JMJD2C and JMJD2D. JMJD2A is a trimethylation-specific demethylase and functions as a transcriptional repressor. JMJD2A interacts with pRb and class one histone deacetylases to mediate repression of E2F-regulated promoters.
- 基因ID
- 9682
- NCBI登录号
- NP_055478
- UniProt
- O75164
- 途径
- Warburg Effect
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