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Recombinant PD-L1 抗体 (C-Term)

PD-L1 适用: 人 WB, IHC, IP, IF (p), IF/ICC, mIF 宿主: 兔 Monoclonal BLR020E unconjugated Recombinant Antibody
产品编号 ABIN7454042
发货至: 中国
  • 抗原 See all PD-L1 抗体
    PD-L1 (CD274 (PD-L1))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 29
    • 16
    • 15
    • 12
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    • 9
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    • 5
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    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
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    • 1
    • 1
    • 1
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    C-Term
    适用
    • 165
    • 114
    • 62
    • 6
    • 5
    • 5
    • 5
    • 1
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    宿主
    • 130
    • 54
    • 19
    • 4
    • 2
    • 1
    克隆类型
    • 113
    • 95
    • 2
    单克隆
    标记
    • 91
    • 15
    • 14
    • 11
    • 8
    • 5
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
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    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
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    • 1
    • 1
    This PD-L1 antibody is un-conjugated
    应用范围
    • 132
    • 103
    • 56
    • 40
    • 35
    • 27
    • 16
    • 16
    • 14
    • 12
    • 10
    • 7
    • 6
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    • 1
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    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (fixed cells) (IF/ICC), Multiplex Immunofluorescence (mIF)
    原理
    Rabbit anti-PD-L1 Recombinant Monoclonal Antibody [BLR020E]
    免疫原
    between AA 250 to 290 (C-term)
    克隆位点
    BLR020E
    亚型
    IgG
    Top Product
    Discover our top product PD-L1 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    PD-L1 (CD274 (PD-L1))
    别名
    PD-L1 (PD-L1 产品)
    别名
    B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody
    背景
    Background: PD-L1 is an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. PD-L1 is a type I transmembrane protein that has immunoglobulin V-like and C-like domains. Interaction of this ligand with its receptor inhibits T-cell activation and cytokine production. During infection or inflammation of normal tissue, this interaction is important for preventing autoimmunity by maintaining homeostasis of the immune response. In tumor microenvironments, this interaction provides an immune escape for tumor cells through cytotoxic T-cell inactivation. Expression of this gene in tumor cells is considered to be prognostic in many types of human malignancies, including colon cancer and renal cell carcinoma [taken from NCBI Entrez Gene (Gene ID: 55193)].
    基因ID
    29126
    NCBI登录号
    NP_054862
    UniProt
    Q9NZQ7
    途径
    Cancer Immune Checkpoints
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