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Recombinant UBQLN4 抗体 (AA 2-601)

UBQLN4 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Monoclonal BLR145J unconjugated Recombinant Antibody
产品编号 ABIN7453990
发货至: 中国
  • 抗原 See all UBQLN4 抗体
    UBQLN4 (Ubiquilin 4 (UBQLN4))
    抗体类型
    Recombinant Antibody
    抗原表位
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 2-601
    适用
    • 21
    • 15
    • 13
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    宿主
    • 21
    克隆类型
    • 20
    • 1
    单克隆
    标记
    • 14
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This UBQLN4 antibody is un-conjugated
    应用范围
    • 14
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), Immunocytochemistry (ICC)
    原理
    Rabbit anti-UBQLN4/CIP75/Ubiquilin 4 Recombinant Monoclonal Antibody [BLR145J]
    免疫原
    residues 2-601 (full length)
    克隆位点
    BLR145J
    亚型
    IgG
    Top Product
    Discover our top product UBQLN4 Primary Antibody
  • 应用备注
    Optimal working dilution should be determined by the investigator.
    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Borate Buffered Saline (BBS) pH 8.2 with 0.09 % Sodium Azide, BSA-Free
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    UBQLN4 (Ubiquilin 4 (UBQLN4))
    别名
    UBQLN4/CIP75/Ubiquilin 4 (UBQLN4 产品)
    别名
    a1u antibody, cip75 antibody, ubin antibody, ubiquilin-4 antibody, A1U antibody, A1Up antibody, C1orf6 antibody, CIP75 antibody, UBIN antibody, A1u antibody, AI663987 antibody, RGD1308273 antibody, ubiquilin 4 L homeolog antibody, ubiquilin 4 antibody, ubqln4.L antibody, ubqln4 antibody, UBQLN4 antibody, Ubqln4 antibody
    背景
    Background: Ubiquilin-4 (UBQLN4) plays a role in the regulation of protein degradation via the ubiquitin-proteasome system (UPS). It mediates the proteasomal targeting of misfolded or accumulated proteins for degradation by binding (via UBA domain) to their polyubiquitin chains and by interacting (via ubiquitin-like domain) with the subunits of the proteasome. UBQLN4 Plays a role in the regulation of the proteasomal degradation of non-ubiquitinated GJA1 (By similarity). It acts as an adapter protein that recruits UBQLN1 to the autophagy machinery and mediates the association of UBQLN1 with autophagosomes and the autophagy-related protein LC3 (MAP1LC3A/B/C) and may assist in the maturation of autophagosomes to autolysosomes by mediating autophagosome-lysosome fusion (PubMed:23459205) [taken from NCBI Entrez Gene (Gene ID: 56893)].
    基因ID
    56893
    NCBI登录号
    NP_064516
    UniProt
    Q9NRR5
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