ERCC5 抗体 (AA 650-700)
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- 抗原 See all ERCC5 抗体
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
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抗原表位
- AA 650-700
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ERCC5 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-ERCC5/XPG Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 650 and 700
- 亚型
- IgG
- Top Product
- Discover our top product ERCC5 Primary Antibody
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- 应用备注
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IHC: 1:100 to 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- ERCC5 (DNA Repair Protein Complementing XP-G Cells (ERCC5))
- 别名
- ERCC5/XPG (ERCC5 产品)
- 别名
- COFS3 antibody, ERCM2 antibody, UVDR antibody, XPG antibody, XPGC antibody, cofs3 antibody, ercm2 antibody, uvdr antibody, xpg antibody, xpgc antibody, Xpg antibody, ERCC excision repair 5, endonuclease antibody, excision repair cross-complementation group 5 L homeolog antibody, excision repair cross-complementing rodent repair deficiency, complementation group 5 antibody, ERCC5 antibody, ercc5.L antibody, Ercc5 antibody
- 背景
- Background: ERCC5 is a single-stranded DNA endonuclease involved in DNA excision repair. ERCC5 is an important component of the nucleotide excision repair (NER) pathway which is critical to the repair of DNA lesions caused by exposure to UV light. Defects in ERCC5 are the cause of xeroderma pigmentosum, an autosomal recessive disease characterized by a hypersensitivity to sunlight and a high predisposition to cancer on UV-exposed areas.
- 基因ID
- 2073
- NCBI登录号
- NP_000114
- UniProt
- P28715
- 途径
- DNA Damage Repair
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