RNF40 抗体 (AA 540-590)
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- 抗原 See all RNF40 抗体
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
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抗原表位
- AA 540-590
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RNF40 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-RNF40 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 540 and 590
- 亚型
- IgG
- Top Product
- Discover our top product RNF40 Primary Antibody
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- 应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- RNF40 (Ring Finger Protein 40, E3 Ubiquitin Protein Ligase (RNF40))
- 别名
- RNF40 (RNF40 产品)
- 别名
- AI848422 antibody, mKIAA0661 antibody, BRE1B antibody, RBP95 antibody, STARING antibody, ring finger protein 40 antibody, RNF40 antibody, Rnf40 antibody
- 背景
- Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes. Targeting of proteins by ubiquitination occurs in three main steps that involve the activation of ubiquitin by E1 enzymes, the carrying of ubiquitin to the target protein by E2 enzymes and the ligation of ubiquitin to the target protein by E3 enzymes. Ring finger protein 40 (RNF40) is a member of the RING type E3 ubiquitin ligases. RNF40 forms a complex with RNF20 to carry out H2B monoubiquitination in association with hPAF and the UbcH6 ubiquitin E2-conjugating enzyme. H2B monoubiquitination by RN40/RNF20 has been shown to be associated with increased H3 methylation and gene transcription.
- 基因ID
- 9810
- NCBI登录号
- NP_055586
- UniProt
- O75150
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