FLII 抗体 (AA 425-475)
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- 抗原 See all FLII 抗体
- FLII (Flightless I Homolog (FLII))
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抗原表位
- AA 425-475
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This FLII antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-Flightless-1 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 425 and 475
- 亚型
- IgG
- Top Product
- Discover our top product FLII Primary Antibody
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- 应用备注
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IHC: 1:100 - 1:500. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- FLII (Flightless I Homolog (FLII))
- 别名
- Flightless-1 (FLII 产品)
- 别名
- FLI antibody, FLIL antibody, Fli1 antibody, 3632430F08Rik antibody, Fliih antibody, im:7141769 antibody, DKFZp459O043 antibody, flightless antibody, FLII, actin remodeling protein antibody, flightless I actin binding protein antibody, protein flightless-1 homolog antibody, FLII, actin remodeling protein S homeolog antibody, Protein flightless-1 homolog antibody, FLII antibody, Flii antibody, flii antibody, LOC585336 antibody, LOC100640615 antibody, flii.S antibody, fli-1 antibody
- 背景
- Background: Flightless-1 is the human homolog of the drosophila flightless (fli1), a gene required for proper development of flight muscles and essential to embryonic development. It is a member of the gelsolin family of actin-binding proteins, and is highly conserved among vertebrates and invertebrates. The actin-remodeling activity of flightless-1 may have multiple roles in the cell. Studies in transgenic mice indicate a role in wound healing that may involve the regulation of cell migration and proliferation. Flightless-1 has also been found to be associated with complexes involved in transcriptional regulation. It associates with CARM1, a protein arginine methyltransferase, and may function as a nuclear receptor coactivator via this interaction. It has also been shown to associate with the BAF53a subunit of the SWI/SNF-like chromatin remodeling complexes.
- 基因ID
- 2314
- NCBI登录号
- NP_002009
- UniProt
- Q13045
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