CHD8 抗体 (AA 325-350)
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- 抗原 See all CHD8 抗体
- CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))
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抗原表位
- AA 325-350
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This CHD8 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-CHD8 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 325 and 350
- 亚型
- IgG
- Top Product
- Discover our top product CHD8 Primary Antibody
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- 应用备注
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IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- CHD8 (Chromodomain Helicase DNA Binding Protein 8 (CHD8))
- 别名
- CHD8 (CHD8 产品)
- 别名
- CHD8 antibody, Chd8 antibody, CHD-8 antibody, AUTS18 antibody, HELSNF1 antibody, 5830451P18Rik antibody, AU015341 antibody, Duplin antibody, mKIAA1564 antibody, fi45h08 antibody, si:ch211-10e2.6 antibody, wu:fi45h08 antibody, chromodomain helicase DNA binding protein 8 antibody, CHD8 antibody, chd8 antibody, Chd8 antibody
- 背景
- Background: CHD8 is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD8 has been reported to interact with duplin, a protein involved in the wnt signaling pathway, and CTCF, a protein involved in heterochromatin formation.
- 基因ID
- 57680
- NCBI登录号
- NP_065971
- UniProt
- Q9HCK8
- 途径
- Chromatin Binding
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