PSMD1 抗体 (AA 903-953)
-
- 抗原 See all PSMD1 抗体
- PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))
-
抗原表位
- AA 903-953
-
适用
- 人, 小鼠
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This PSMD1 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-PSMD1 Antibody, Affinity Purified
- 预测反应
- Rat,Chicken,Orangutan
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 903 and 953
- 亚型
- IgG
- Top Product
- Discover our top product PSMD1 Primary Antibody
-
-
- 应用备注
-
IHC: 1:1,000 to 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: 1:10,000 - 1:25,000
- 限制
- 仅限研究用
-
- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
-
- 抗原
- PSMD1 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 1 (PSMD1))
- 别名
- PSMD1 (PSMD1 产品)
- 别名
- P112 antibody, Rpn2 antibody, S1 antibody, 2410026J11Rik antibody, zgc:55818 antibody, psmd1 antibody, proteasome 26S subunit, non-ATPase 1 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 1 antibody, proteasome 26S subunit, non-ATPase 1 L homeolog antibody, PSMD1 antibody, Psmd1 antibody, psmd1 antibody, psmd1.L antibody
- 背景
- Background: PSMD1 [proteasome (prosome, macropain) 26S subunit, non-ATPase, 1] is a subunit of the 26 S proteasome. The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD1 is the largest non-ATPase subunit of the 19S regulator lid, which is responsible for substrate recognition and binding [taken from NCBI Entrez Gene (Gene ID: 5707)].
- 基因ID
- 5707
- NCBI登录号
- NP_002798
- UniProt
- Q99460
- 途径
- Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway
-