RBM17 抗体 (AA 25-75)
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- 抗原 See all RBM17 抗体
- RBM17 (RNA Binding Motif Protein 17 (RBM17))
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抗原表位
- AA 25-75
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This RBM17 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-SPF45 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 25 and 75
- 亚型
- IgG
- Top Product
- Discover our top product RBM17 Primary Antibody
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- 应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 10 μg/mg lysate
WB: Not recommended. Use rabbit anti-SPF45 antibody ABIN7453790.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- RBM17 (RNA Binding Motif Protein 17 (RBM17))
- 别名
- SPF45 (RBM17 产品)
- 别名
- zgc:55840 antibody, SPF45 antibody, 2700027J02Rik antibody, RNA binding motif protein 17 antibody, RNA binding motif protein 17 L homeolog antibody, Rbm17 antibody, rbm17 antibody, RBM17 antibody, rbm17.L antibody
- 背景
- Background: Splicing factor 45 (SPF45) is an RNA splicing factor that binds to the single stranded 3'AG at the exon/intron border and promotes its utilization in the second catalytic step. SPF45 is involved in the regulation of alternative splicing and the utilization of cryptic splice sites. It has been shown to promote the utilization of a cryptic splice site created by the beta-110 mutation in the human beta-thalassemia gene. The resulting frameshift leads to sickle cell anemia [taken from the Universal Protein Resource (UniProt) Q96125].
- 基因ID
- 84991
- NCBI登录号
- NP_116294
- UniProt
- Q96I25
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