MAPKAP1 抗体 (C-Term)
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- 抗原 See all MAPKAP1 抗体
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
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抗原表位
- C-Term
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This MAPKAP1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-Sin1 Antibody, Affinity Purified
- 预测反应
- Mouse,Rat,Chicken,Sheep,Bovine,Orangutan
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 470 and C-term
- 亚型
- IgG
- Top Product
- Discover our top product MAPKAP1 Primary Antibody
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anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 8-236) antibody
MAPKAP1 适用: 人 WB, IHC, IP, ICC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 100-150) antibodyMAPKAP1 适用: 人, 小鼠, 大鼠, 犬, Cow WB, IHC, IHC (p) 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 370-486) antibodyMAPKAP1 适用: 人 WB, IHC 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 1-290) antibodyMAPKAP1 适用: 人 WB, ELISA 宿主: 兔 Polyclonal unconjugated
anti-Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1) (AA 85-102) antibodyMAPKAP1 适用: 人, 小鼠, 大鼠, 犬, Cow, 小鸡, 马, 绵羊, Bat, 猴, 兔, 斑马鱼 WB 宿主: 兔 Polyclonal unconjugated
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- 应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- MAPKAP1 (Mitogen-Activated Protein Kinase Associated Protein 1 (MAPKAP1))
- 别名
- Sin1 (MAPKAP1 产品)
- 别名
- CG10105 antibody, Dmel\\CG10105 antibody, dSin1 antibody, sin1 antibody, MAPKAP1 antibody, im:7143088 antibody, si:ch73-242f23.1 antibody, mip1 antibody, sin1b antibody, sin1g antibody, MGC53034 antibody, JC310 antibody, MIP1 antibody, SIN1 antibody, SIN1b antibody, SIN1g antibody, AI591529 antibody, D230039K05Rik antibody, Sin1 antibody, SAPK-interacting protein 1 antibody, mitogen-activated protein kinase associated protein 1 antibody, mitogen-activated protein kinase associated protein 1 L homeolog antibody, Sin1 antibody, MAPKAP1 antibody, mapkap1 antibody, Mapkap1 antibody, mapkap1.L antibody
- 背景
- Background: Stress-activated map kinase-interacting protein 1 (Sin1) is highly similar to the yeast stress- activated protein kinase SIN1. Sin1 is an essential mTORC2 subunit that is required to act as the PDK2 that phosphorylates Akt/PKB at Ser 473. Sin1 has been implicated as a scaffolding protein. Sin1 is required for rictor binding in the mTORC2 complex. Sin1 has also been shown to be important to the SAPK (stress-activated kinase) signaling pathway and in the nucleus may act as a scaffold between ATF-2 and p38 to facilitate p38-induced phosphorylation of ATF-2. Sin1 is also found to form a complex with c-Jun N-terminal kinase (JNK) and may similarly function as a scaffolding protein in JNK signaling.
- 基因ID
- 79109
- NCBI登录号
- NP_001006618
- UniProt
- Q9BPZ7
- 途径
- PI3K-Akt Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Skeletal Muscle Fiber Development, CXCR4-mediated Signaling Events
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