NPAT 抗体 (AA 1377-1427)
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- 抗原 See all NPAT 抗体
- NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))
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抗原表位
- AA 1377-1427
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This NPAT antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Formalin-fixed Paraffin-embedded Sections) (IHC (fp))
- 原理
- Rabbit anti-NPAT Antibody, Affinity Purified
- 预测反应
- Mouse
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 1377 and 1427
- 亚型
- IgG
- Top Product
- Discover our top product NPAT Primary Antibody
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- 应用备注
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IHC: 1:1,000 - 1:5,000. Epitope retrieval with citrate buffer pH 6.0 is recommended for FFPE tissue sections.
IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- NPAT (Nuclear Protein, Ataxia-Telangiectasia Locus (NPAT))
- 别名
- NPAT (NPAT 产品)
- 别名
- NPAT-like antibody, im:6901964 antibody, DKFZp469B186 antibody, 6820401K01 antibody, AI427561 antibody, BB112559 antibody, E14 antibody, E14/NPAT antibody, p220 antibody, nuclear protein, co-activator of histone transcription antibody, nuclear protein, coactivator of histone transcription antibody, protein NPAT antibody, nuclear protein, ataxia-telangiectasia locus antibody, nuclear protein in the AT region antibody, nuclear protein, ataxia-telangiectasia locus S homeolog antibody, Npat antibody, NPAT antibody, LOC489420 antibody, npat antibody, LOC100286556 antibody, LOC100402032 antibody, LOC100480887 antibody, LOC100540521 antibody, LOC100561473 antibody, LOC100627195 antibody, npat.S antibody
- 背景
- Background: NPAT (nuclear protein of the ataxia telangiectasia mutated locus) is required for progression through the G1 and S phases of the cell cycle and for S phase entry. It activates transcription of the histone H2A, histone H2B, histone H3 and histone H4 genes in conjunction with MIZF. NPAT also positively regulates the ATM, MIZF and PRKDC promoters. Transcriptional activation may be accomplished at least in part by the recruitment of the NuA4 histone acetyltransferase (HAT) complex to target gene promoters [taken from the Universal Protein Resource (UniProt) ww.uniprot.org/uniprot/Q14207].
- 基因ID
- 4863
- NCBI登录号
- NP_002510
- UniProt
- Q14207
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