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SMG1 抗体 (AA 1625-1675)

SMG1 适用: 人 WB 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452857
发货至: 中国
  • 抗原 See all SMG1 抗体
    SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))
    抗原表位
    • 7
    • 6
    • 3
    • 2
    • 1
    • 1
    • 1
    AA 1625-1675
    适用
    • 22
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    宿主
    • 17
    • 4
    克隆类型
    • 18
    • 4
    多克隆
    标记
    • 12
    • 2
    • 2
    • 2
    • 2
    • 2
    This SMG1 antibody is un-conjugated
    应用范围
    • 17
    • 15
    • 9
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    原理
    Rabbit anti-SMG1 Antibody, Affinity Purified
    预测反应
    Mouse
    纯化方法
    Affinity Purified
    免疫原
    between AA 1625 and 1675
    亚型
    IgG
    Top Product
    Discover our top product SMG1 Primary Antibody
  • 应用备注

    IP: Not recommended. A300-394A is recommended.

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    SMG1 (pi-3-Kinase-Related Kinase SMG-1 (SMG1))
    别名
    SMG1 (SMG1 产品)
    别名
    61E3.4 antibody, ATX antibody, LIP antibody, 2610207I05Rik antibody, 5430435M13Rik antibody, C130002K18Rik antibody, mKIAA0421 antibody, zgc:152973 antibody, SMG1, nonsense mediated mRNA decay associated PI3K related kinase antibody, SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans) antibody, SMG1 phosphatidylinositol 3-kinase-related kinase antibody, Serine/threonine-protein kinase smg-1 antibody, SMG1 antibody, Smg1 antibody, smg1 antibody, smg-1 antibody
    背景
    Background: SMG1 is a PIKK (phosphoinositide 3-kinase related kinases) protein kinase that plays a key role in RNA surveillance via nonsense-mediated mRNA decay (NMD). SMG1 phosphorylates Upf1, a factor that possesses RNA helicase activity and is also central to NMD. SMG1 and UPF-1 have been shown to exist in a complex with the translation termination release factors eRF3, and eRF1. This complex has been termed SURF and associates with the exon junction complex (EJC) to function in the recognition of premature termination codons in aberrant RNAs to trigger NMD.
    基因ID
    23049
    UniProt
    Q96Q15, Q96QV0
    途径
    Inositol Metabolic Process
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