ZNF207 抗体 (AA 428-478)
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- 抗原 See all ZNF207 抗体
- ZNF207 (Zinc Finger Protein 207 (ZNF207))
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抗原表位
- AA 428-478
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This ZNF207 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-ZNF207 Antibody, Affinity Purified
- 预测反应
- Orangutan
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 428 and 478
- 亚型
- IgG
- Top Product
- Discover our top product ZNF207 Primary Antibody
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- 应用备注
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- ZNF207 (Zinc Finger Protein 207 (ZNF207))
- 别名
- ZNF207 (ZNF207 产品)
- 别名
- MGC116398 antibody, 4m77 antibody, MGC75627 antibody, ZNF207 antibody, Zfp207 antibody, wu:fb50g07 antibody, wu:fc17a09 antibody, wu:fc17a10 antibody, wu:fj12e11 antibody, zgc:56601 antibody, znf207 antibody, wu:fa03f07 antibody, wu:fb51h09 antibody, zgc:77832 antibody, zinc finger protein 207 antibody, zinc finger protein 207, b antibody, zinc finger protein 207 S homeolog antibody, zinc finger protein 207, a antibody, Zfp207 antibody, znf207 antibody, ZNF207 antibody, znf207b antibody, znf207.S antibody, znf207a antibody
- 背景
- Background: ZNF207 is a kinetochore- and microtubule-binding protein that plays a key role in spindle assembly. ZNF207/BuGZ is mainly composed of disordered low-complexity regions and undergoes phase transition or coacervation to form temperature-dependent liquid droplets. Coacervation promotes microtubule bundling and concentrates tubulin, promoting microtubule polymerization and assembly of spindle and spindle matrix by concentrating its building blocks. Also acts as a regulator of mitotic chromosome alignment by mediating the stability and kinetochore loading of BUB3. Mechanisms by which BUB3 is protected are unclear: according to a first report, ZNF207/BuGZ may act by blocking ubiquitination and proteasomal degradation of BUB3 . According to another report, the stabilization is independent of the proteasome. [taken from the Universal Protein Resource (UniProt) O43670].
- 基因ID
- 7756
- UniProt
- O43670
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