电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

TBC1D23 抗体 (AA 525-575)

TBC1D23 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452842
发货至: 中国
  • 抗原 See all TBC1D23 products
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    抗原表位
    • 4
    • 1
    • 1
    • 1
    AA 525-575
    适用
    • 9
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 9
    克隆类型
    • 9
    多克隆
    标记
    • 6
    • 1
    • 1
    • 1
    This TBC1D23 antibody is un-conjugated
    应用范围
    • 5
    • 5
    • 4
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-TBC1D23 Antibody, Affinity Purified
    预测反应
    Mouse,Zebrafish,X. laevis,Chicken,Orangutan
    纯化方法
    Affinity Purified
    免疫原
    between AA 525 and 575
    亚型
    IgG
  • 应用备注

    IP: 50-100 μL/mg lysate

    WB: 1:10,000 - 1:25,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    TBC1D23 (TBC1 Domain Family, Member 23 (TBC1D23))
    别名
    TBC1D23 (TBC1D23 产品)
    别名
    RGD1307925 antibody, NS4ATP1 antibody, 4930451A13Rik antibody, AU015720 antibody, AU043671 antibody, AU043778 antibody, D030022P07Rik antibody, W51689 antibody, zgc:63756 antibody, TBC1 domain family, member 23 antibody, TBC1 domain family member 23 antibody, Tbc1d23 antibody, TBC1D23 antibody, tbc1d23 antibody
    背景
    Background: TBC1D23 is a putative Rab GTPase-activating protein which plays a role in vesicular trafficking and is involved in endosome-to-Golgi trafficking. Acts as a bridging protein by binding simultaneously to golgins, including GOLGA1 and GOLGA4, located at the trans-Golgi, and to the WASH complex, located on endosome-derived vesicles. Together with WDR11 complex facilitates the golgin-mediated capture of vesicles generated using AP-1. TBC1D23 also plays a role in brain development, including in cortical neuron positioning. May also be important for neurite outgrowth, possibly through its involvement in membrane trafficking and cargo delivery, 2 processes that are essential for axonal and dendritic growth. May act as a general inhibitor of innate immunity signaling, strongly inhibiting multiple TLR and dectin/CLEC7A-signaling pathways. Does not alter initial activation events, but instead affects maintenance of inflammatory gene expression several hours after bacterial lipopolysaccharide (LPS) challenge. [taken from the Universal Protein Resource (UniProt) Q9NUY8].
    基因ID
    55773
    UniProt
    Q9NUY8
You are here:
客服