C17ORF85 抗体 (AA 25-75)
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- 抗原 See all C17ORF85 products
- C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))
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抗原表位
- AA 25-75
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This C17ORF85 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-C17orf85 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 25 and 75
- 亚型
- IgG
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- 应用备注
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IP: 50-100 μL/mg lysate
WB: 1:10,000 - 1:25,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))
- 别名
- C17orf85 (C17ORF85 产品)
- 别名
- ELG antibody, HSA277841 antibody, C130061O14Rik antibody, C78393 antibody, nuclear cap binding subunit 3 antibody, nuclear cap binding subunit 3 L homeolog antibody, NCBP3 antibody, Ncbp3 antibody, ncbp3.L antibody
- 背景
- Background: C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) Q53F19].
- 基因ID
- 55421
- UniProt
- Q53F19
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