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C17ORF85 抗体 (AA 25-75)

C17ORF85 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452805
发货至: 中国
  • 抗原 See all C17ORF85 products
    C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))
    抗原表位
    • 1
    • 1
    • 1
    AA 25-75
    适用
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 4
    克隆类型
    • 4
    多克隆
    标记
    • 4
    This C17ORF85 antibody is un-conjugated
    应用范围
    • 4
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-C17orf85 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 25 and 75
    亚型
    IgG
  • 应用备注

    IP: 50-100 μL/mg lysate

    WB: 1:10,000 - 1:25,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    C17ORF85 (Chromosome 17 Open Reading Frame 85 (C17ORF85))
    别名
    C17orf85 (C17ORF85 产品)
    别名
    ELG antibody, HSA277841 antibody, C130061O14Rik antibody, C78393 antibody, nuclear cap binding subunit 3 antibody, nuclear cap binding subunit 3 L homeolog antibody, NCBP3 antibody, Ncbp3 antibody, ncbp3.L antibody
    背景
    Background: C17orf85 (NCBP3) associates with NCBP1/CBP80 to form an alternative cap-binding complex (CBC) which plays a key role in mRNA export. C17orf85 (NCBP3) serves as adapter protein linking the capped RNAs (m7GpppG-capped RNA) to NCBP1/CBP80. Unlike the conventional CBC with NCBP2 which binds both small nuclear RNA (snRNA) and messenger (mRNA) and is involved in their export from the nucleus, the alternative CBC with C17orf85 (NCBP3) does not bind snRNA and associates only with mRNA thereby playing a role in only mRNA export. The alternative CBC is particularly important in cellular stress situations such as virus infections and the C17orf85 (NCBP3) activity is critical to inhibit virus growth. [taken from the Universal Protein Resource (UniProt) Q53F19].
    基因ID
    55421
    UniProt
    Q53F19
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