KIAA1524 抗体 (N-Term)
-
- 抗原 See all KIAA1524 抗体
- KIAA1524
-
抗原表位
- N-Term
-
适用
- 人, 小鼠
-
宿主
- 小鼠
-
克隆类型
- 单克隆
-
标记
- This KIAA1524 antibody is un-conjugated
-
应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Mouse anti-CIP2A Monoclonal Antibody, Affinity Purified [2A1-9A4]
- 纯化方法
- Affinity Purified
- 免疫原
- Amino terminal one-third of the CIP2A (GeneID 57650) recombinant protein
- 克隆位点
- 2A1-9A4
- 亚型
- IgG
- Top Product
- Discover our top product KIAA1524 Primary Antibody
-
-
- 应用备注
-
IP: 20 μL/mg lysate
WB: 17:40:00
- 限制
- 仅限研究用
-
- 浓度
- 40 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
-
- 抗原
- KIAA1524
- 别名
- CIP2A (KIAA1524 产品)
- 别名
- CIP2A antibody, p90 antibody, AA408511 antibody, AU018569 antibody, Cip2a antibody, Kiaa1524 antibody, KIAA1524 antibody, LOC100222895 antibody, RGD1310335 antibody, cell proliferation regulating inhibitor of protein phosphatase 2A antibody, RIKEN cDNA C330027C09 gene antibody, KIAA1524 antibody, cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog antibody, CONSTANS interacting protein 2a antibody, CIP2A antibody, C330027C09Rik antibody, KIAA1524 antibody, cip2a.L antibody, CIP2a antibody, cip2a antibody, Cip2a antibody
- 背景
- Background: CIP2A (cancerous inhibitor of PP2A) was originally identified as p90, a cytoplasmic autoantigen found in the serum from a cancer patient. It was later described as a protein that interacted with the c-myc oncogene and functioned as an inhibitor of protein phosphatase 2A (PP2A) activity. Inhibition of PP2A phosphatase activity by CIP2A prevents c-myc phosphorylation and counteracts c-myc proteolytic degradation, thereby stabilizing c-myc and promoting cell growth and transformation. CIP2A is found to be overexpressed in some human malignancies and is thus classified as an oncogene that may be an important contributor to tumor formation.
- 基因ID
- 57650
- NCBI登录号
- NP_065941
- UniProt
- Q8TCG1
-