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DUSP12 抗体 (AA 1-50)

DUSP12 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452603
发货至: 中国
  • 抗原 See all DUSP12 抗体
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    抗原表位
    • 7
    • 6
    • 6
    • 6
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-50
    适用
    • 35
    • 13
    • 5
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 32
    • 3
    克隆类型
    • 35
    多克隆
    标记
    • 18
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DUSP12 antibody is un-conjugated
    应用范围
    • 27
    • 16
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-DUSP12 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    Between AA 1 and 50
    亚型
    IgG
    Top Product
    Discover our top product DUSP12 Primary Antibody
  • 应用备注

    IP: 20 μL/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    DUSP12 (Dual Specificity Phosphatase 12 (DUSP12))
    别名
    DUSP12 (DUSP12 产品)
    别名
    DUSP12 antibody, dusp12 antibody, zgc:114069 antibody, MGC154526 antibody, DUSP1 antibody, YVH1 antibody, 1190004O14Rik antibody, AA027408 antibody, AW049275 antibody, ESTM36 antibody, LMW-DSP4 antibody, T-DSP4 antibody, VH1 antibody, mVH1 antibody, GKAP antibody, dual specificity phosphatase 12 antibody, dual specificity phosphatase 12 L homeolog antibody, Dual specificity protein phosphatase 12 antibody, dual specificity protein phosphatase 12 antibody, DUSP12 antibody, dusp12 antibody, dusp12.L antibody, GL50803_36315 antibody, MGYG_01770 antibody, Dusp12 antibody
    背景
    Background: Dual specificity protein phosphatase 12 (DUSP12) is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. DUSP12 is the human ortholog of the Saccharomyces cerevisiae YVH1 protein tyrosine phosphatase. It is localized predominantly in the nucleus, and is novel in that it contains, and is regulated by a zinc finger domain [taken from NCBI Entrez Gene (Gene ID: 11266)].
    基因ID
    11266
    UniProt
    Q9UNI6
    途径
    Regulation of Carbohydrate Metabolic Process
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