Mahogunin RING Finger Protein 1 抗体 (AA 505-555)
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- 抗原 See all Mahogunin RING Finger Protein 1 (MGRN1) 抗体
- Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
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抗原表位
- AA 505-555
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This Mahogunin RING Finger Protein 1 antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-MGRN1 Antibody, Affinity Purified
- 预测反应
- Gorilla,Chimpanzee
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 505 and 555
- 亚型
- IgG
- Top Product
- Discover our top product MGRN1 Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- Mahogunin RING Finger Protein 1 (MGRN1) (Mahogunin, Ring Finger 1 (MGRN1))
- 别名
- MGRN1 (MGRN1 产品)
- 别名
- RNF156 antibody, 2610042J20Rik antibody, mKIAA0544 antibody, md antibody, nc antibody, RGD1311862 antibody, mgrn1 antibody, wu:fi38c03 antibody, zgc:55978 antibody, mahogunin ring finger 1 antibody, mahogunin, ring finger 1 antibody, mahogunin ring finger 1, E3 ubiquitin protein ligase S homeolog antibody, mahogunin ring finger 1, E3 ubiquitin protein ligase antibody, mahogunin, ring finger 1a antibody, MGRN1 antibody, Mgrn1 antibody, mgrn1.S antibody, mgrn1 antibody, mgrn1a antibody
- 背景
- Background: MGRN1 (mahogunin RING finger protein 1) is an E3 ubiquitin-protein ligase that mediates monoubiquitination at multiple sites of TSG101 in the presence of UBE2D1, but not of UBE2G1, nor UBE2H. MGRN1 plays a role in the regulation of endosome-to-lysosome trafficking. It impairs MC1R- and MC4R-signaling by competing with GNAS-binding to MCRs and inhibiting agonist-induced cAMP production but does not promote MC1R ubiquitination [taken from the Universal Protein Resource (UniProt) O60291].
- 基因ID
- 23295
- NCBI登录号
- NP_001135761
- UniProt
- O60291
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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