CSTF2T 抗体 (AA 225-275)
-
- 抗原 See all CSTF2T 抗体
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
-
抗原表位
- AA 225-275
-
适用
- 人
-
宿主
- 兔
-
克隆类型
- 多克隆
-
标记
- This CSTF2T antibody is un-conjugated
-
应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-CSTF2T/TauCSTF64 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 225 and 275
- 亚型
- IgG
- Top Product
- Discover our top product CSTF2T Primary Antibody
-
-
- 应用备注
-
IP: 2 - 5 μg/mg lysate
WB: Not recommended. Use rabbit anti-CSTF2T/TauCSTF64 antibody A301-487A.
- 限制
- 仅限研究用
-
- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
-
- 抗原
- CSTF2T (Cleavage Stimulation Factor, 3' Pre-RNA, Subunit 2, 64kDa, tau Variant (CSTF2T))
- 别名
- CSTF2T/TauCSTF64 (CSTF2T 产品)
- 别名
- 64kDa antibody, C77975 antibody, tCstF-64 antibody, tauCstF-64 antibody, CstF-64T antibody, cleavage stimulation factor, 3' pre-RNA subunit 2, tau antibody, cleavage stimulation factor subunit 2 tau variant antibody, cleavage stimulation factor subunit 2, tau variant antibody, Cstf2t antibody, CSTF2T antibody
- 背景
- Background: CSTF2T, also known as tauCSTF-64, is a paralog of CstF-64, a component of the cleavage stimulation factor (CstF) that processes 3'-end formation and polyadenylation of mRNAs. The human CSTF2T/TauCSTF64 gene is located at 10q22-23, a site associated with neurological problems and male infertility. CSTF2T is expressed in all tissues and throughout meiosis in male germ cells. CstF-64 is also expressed ubiquitously, however because it is located on the X chromosome, its expression is temporarily silenced in germ cells by meiotic sex chromosome inactivation. During this inactivation, it is hypothesized that CSTF2T/TauCSTF64 can compensate for the loss of CstfF-64 expression. Recently, targeted disruption of CSTF2T/TauCSTF64 in mice has been shown to cause aberrant spermatogenesis and infertility providing more evidence for its importance in spermatogenesis.
- 基因ID
- 23283
- NCBI登录号
- NP_056050
- UniProt
- Q9H0L4
-