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BRISC and BRCA1 A Complex Member 1 (BABAM1) (AA 1-50) 抗体

BABAM1 适用: 人 IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7452241
发货至: 中国
  • 抗原 See all BRISC and BRCA1 A Complex Member 1 (BABAM1) 抗体
    BRISC and BRCA1 A Complex Member 1 (BABAM1)
    抗原表位
    • 10
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    AA 1-50
    适用
    • 26
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    宿主
    • 21
    • 4
    • 1
    克隆类型
    • 24
    • 2
    多克隆
    标记
    • 16
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    非结合性
    应用范围
    • 24
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    Immunoprecipitation (IP)
    原理
    Rabbit anti-MERIT40 Antibody, Affinity Purified
    预测反应
    Orangutan
    纯化方法
    Affinity Purified
    免疫原
    between AA 1 and 50
    亚型
    IgG
    Top Product
    Discover our top product BABAM1 Primary Antibody
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: Not recommended. ABIN7452241 has not performed satisfactorily when used for WB of MERIT40 in crude preparations (e.g. whole cell lysate). This antibody can be used for WB of enriched (e.g. immunoprecipitated) sources of MERIT40.

    限制
    仅限研究用
  • 浓度
    1000 μg/mL
    缓冲液
    Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    BRISC and BRCA1 A Complex Member 1 (BABAM1)
    别名
    MERIT40 (BABAM1 产品)
    别名
    merit40 antibody, nba1 antibody, zgc:100909 antibody, c19orf62 antibody, C19orf62 antibody, MERIT40 antibody, NBA1 antibody, C7H19orf62 antibody, 5430437P03Rik antibody, Merit40 antibody, BRISC and BRCA1 A complex member 1 antibody, BRISC and BRCA1 A complex member 1 L homeolog antibody, babam1 antibody, BABAM1 antibody, babam1.L antibody, Babam1 antibody
    背景
    Background: MERIT40 (mediator of RAP80 interactions and targeting subunit of 40 kDa) is a component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites and leads to targeting of the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). In the BRCA1-A complex, it is required for the complex integrity and its localization at DSBs. MERIT40 probably also plays a role as a component of the BRISC complex, a multiprotein complex that specifically cleaves 'Lys-63'-linked ubiquitin [taken from the Universal Protein Resource (UniProt) Q9NWV8].
    基因ID
    29086
    NCBI登录号
    NP_054892
    UniProt
    Q9NWV8
    途径
    Positive Regulation of Response to DNA Damage Stimulus
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