SPEN 抗体 (AA 3375-3425)
SPEN
适用: 人
IP
宿主: 兔
Polyclonal
unconjugated
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- 抗原 See all SPEN 抗体
- SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
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抗原表位
- AA 3375-3425
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SPEN antibody is un-conjugated
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应用范围
- Immunoprecipitation (IP)
- 原理
- Rabbit anti-SHARP Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 3375 and 3425
- 亚型
- IgG
- Top Product
- Discover our top product SPEN Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: Not recommended. ABIN7451040 can be used successfully for WB of enriched preparations (e.g. immunoprecipitated) SHARP.
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- SPEN (Spen Homolog, Transcriptional Regulator (SPEN))
- 别名
- SHARP (SPEN 产品)
- 别名
- HIAA0929 antibody, MINT antibody, RBM15C antibody, SHARP antibody, Mint antibody, mKIAA0929 antibody, spen family transcriptional repressor antibody, SPEN homolog, transcriptional regulator (Drosophila) antibody, SPEN antibody, Spen antibody
- 背景
- Background: SHARP functions as a transcriptional repressor by interacting with proteins involved in deacetylation such as the NuRD (nucleosome remodeling) complex. SHARP can also repress transcription by interacting with corepressors such as SMRT/NCoR (silencing mediator for retinoid and thyroid receptors/nuclear receptor corepressor). SHARP is able to suppress transcription through the Notch/RBP-J signaling pathway by competing RBP-J binding with the intracellular domain of Notch.
- 基因ID
- 23013
- NCBI登录号
- NP_055816
- UniProt
- Q96T58
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