USP20 抗体 (AA 863-913)
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- 抗原 See all USP20 抗体
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
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抗原表位
- AA 863-913
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This USP20 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-USP20/VDU2 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 863 and 913
- 亚型
- IgG
- Top Product
- Discover our top product USP20 Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- USP20 (Ubiquitin Specific Peptidase 20 (USP20))
- 别名
- USP20/VDU2 (USP20 产品)
- 别名
- USP20 antibody, vdu2 antibody, lsfr3a antibody, LSFR3A antibody, VDU2 antibody, hVDU2 antibody, 1700055M05Rik antibody, AI467231 antibody, Vdu2 antibody, im:7151955 antibody, zgc:63661 antibody, universal stress protein antibody, ubiquitin specific peptidase 20 antibody, ubiquitin specific peptidase 20 L homeolog antibody, RR_RS15875 antibody, USP20 antibody, usp20 antibody, Usp20 antibody, usp20.L antibody
- 背景
- Background: The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific peptidase 20 (USP20) is a UBP and is also called von-Hippel-Lindau protein (pVHL) interacting deubiquitinating enzyme 2 (VDU2). pVHL is an E3 ubiquitin-ligase that ubiquitinates hypoxia-inducible factor (HIF)-1alpha. USP20/VDU2 functions to specifically deubiquitinate HIF-1alpha to increase expression of HIF-1alpha regulated genes.
- 基因ID
- 10868
- NCBI登录号
- NP_006667
- UniProt
- Q9Y2K6
- 途径
- Regulation of G-Protein Coupled Receptor Protein Signaling
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