TAB2 抗体 (AA 500-550)
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- 抗原 See all TAB2 抗体
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
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抗原表位
- AA 500-550
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适用
- 人, 小鼠
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This TAB2 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-TAB2 Antibody, Affinity Purified
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 500 and 550
- 亚型
- IgG
- Top Product
- Discover our top product TAB2 Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 1000 μg/mL
- 缓冲液
- Tris-citrate/phosphate buffer, pH 7 to 8 containing 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- TAB2 (TGF-beta Activated Kinase 1/MAP3K7 Binding Protein 2 (TAB2))
- 别名
- TAB2 (TAB2 产品)
- 别名
- CHTD2 antibody, MAP3K7IP2 antibody, 1110030N06Rik antibody, A530078N03Rik antibody, Map3k7ip2 antibody, mKIAA0733 antibody, map3k7ip2 antibody, zgc:77446 antibody, TGF-beta activated kinase 1/MAP3K7 binding protein 2 antibody, TAB2 antibody, Tab2 antibody, tab2 antibody
- 背景
- Background: TAB2 (TGF-beta-activated kinase 1and MAP3K7-binding protein 2) functions as an activator of MAP3K7/TAK1, which is required for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. TAB2 forms a kinase complex with TRAF6, MAP3K7 and TAB1, and thus serves as an adaptor linking MAP3K7 and TRAF6. TAB2, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts [taken from NCBI Entrez Gene (GeneID: 23118)].
- 基因ID
- 23118
- NCBI登录号
- NP_055908
- UniProt
- Q9NYJ8
- 途径
- TCR Signaling, TLR signaling, Fc-epsilon Receptor Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Ubiquitin Proteasome Pathway
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