SMARCAL1 抗体 (AA 904-954)
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- 抗原 See all SMARCAL1 抗体
- SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))
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抗原表位
- AA 904-954
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适用
- 人
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宿主
- 兔
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克隆类型
- 多克隆
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标记
- This SMARCAL1 antibody is un-conjugated
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应用范围
- Western Blotting (WB), Immunoprecipitation (IP)
- 原理
- Rabbit anti-SMARCAL1 Antibody, Affinity Purified
- 预测反应
- Bovine
- 纯化方法
- Affinity Purified
- 免疫原
- between AA 904 and 954
- 亚型
- IgG
- Top Product
- Discover our top product SMARCAL1 Primary Antibody
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- 应用备注
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IP: 2 - 5 μg/mg lysate
WB: 1:2,000 - 1:10,000
- 限制
- 仅限研究用
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- 浓度
- 200 μg/mL
- 缓冲液
- Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
- 储存液
- Sodium azide
- 注意事项
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- 储存条件
- 4 °C
- 有效期
- 12 months
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- 抗原
- SMARCAL1 (SWI/SNF Related, Matrix Associated, Actin Dependent Regulator of Chromatin, Subfamily A-Like 1 (SMARCAL1))
- 别名
- SMARCAL1 (SMARCAL1 产品)
- 别名
- SMARCAL1 antibody, im:7145331 antibody, si:ch211-239d11.1 antibody, harp antibody, hharp antibody, 6030401P21Rik antibody, AI851716 antibody, Mharp antibody, HARP antibody, HHARP antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, Swi/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 antibody, SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1 L homeolog antibody, SMARCAL1 antibody, smarcal1 antibody, Smarcal1 antibody, smarcal1.L antibody
- 背景
- Background: The SMARCs (SWI/SNF-related, matrix-associated, actin-dependent regulators of chromatin), and BAFs (BRG1-associated factors), have been identified as components of the mammalian SWI/SNF-like chromatin-remodeling protein complexes. These multi-protein complexes are proposed to function as ATP-driven motors that translocate along DNA and destabilize nucleosomal structures to facilitate transcription factor binding. SMARCAL1 is a member of the SNF2 family. SMARCAL1 is also known as human hep-related protein (HARP) due to its sequence identity with the E. coli RNA polymerase-binding protein HepA. It has been determined that mutations in SMARCAL1 are the cause of Schimke immuno-osseous dysplasia (SIOD), an autosomal-recessive disorder characterized by spondyloepiphyseal dysplasia, renal dysfunction, facial dysmorphism, and T-cell immunodeficiency. The pleiotropic characteristics of SIOD indicate an important role for SMARCAL1 in the regulation of multiple genes that influence the proliferation of chondrocytes, lymphocytes, and spermatozytes, as well as the development of cardiomyocytes and vascular homeostasis.
- 基因ID
- 50485
- NCBI登录号
- NP_054859
- UniProt
- Q9NZC9
- 途径
- Embryonic Body Morphogenesis
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