电话:
+86 (0512) 65829739
传真:
+86 (010) 6788 5057
电子邮件:
orders@antibodies-online.cn

CIZ1 抗体 (AA 325-375)

CIZ1 适用: 人 WB, IP 宿主: 兔 Polyclonal unconjugated
产品编号 ABIN7451704
发货至: 中国
  • 抗原 See all CIZ1 抗体
    CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
    抗原表位
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 325-375
    适用
    • 17
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    宿主
    • 15
    • 1
    • 1
    克隆类型
    • 17
    多克隆
    标记
    • 10
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This CIZ1 antibody is un-conjugated
    应用范围
    • 10
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunoprecipitation (IP)
    原理
    Rabbit anti-CIZ1 Antibody, Affinity Purified
    纯化方法
    Affinity Purified
    免疫原
    between AA 325 and 375
    亚型
    IgG
    Top Product
    Discover our top product CIZ1 Primary Antibody
  • 应用备注

    IP: 2 - 5 μg/mg lysate

    WB: 1:2,000 - 1:10,000

    限制
    仅限研究用
  • 浓度
    200 μg/mL
    缓冲液
    Tris-buffered Saline containing 0.1 % BSA and 0.09 % Sodium Azide
    储存液
    Sodium azide
    注意事项
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    储存条件
    4 °C
    有效期
    12 months
  • 抗原
    CIZ1 (CDKN1A Interacting Zinc Finger Protein 1 (CIZ1))
    别名
    CIZ1 (CIZ1 产品)
    别名
    LSFR1 antibody, NP94 antibody, ZNF356 antibody, CIZ1 antibody, 0610038H21Rik antibody, 2900056O04Rik antibody, ciz1 antibody, wu:fi12g11 antibody, wu:fi27d02 antibody, zgc:66467 antibody, CDKN1A interacting zinc finger protein 1 antibody, cip1-interacting zinc finger protein antibody, cdkn1a interacting zinc finger protein 1b antibody, CIZ1 antibody, LOC464765 antibody, Ciz1 antibody, ciz1b antibody
    背景
    Background: CIZ1 (Cip1 interacting zinc-finger protein) was identified as a protein that associates with the cell-cycle inhibiting protein, p21 (Cip1/Waf1). CIZ1 is a member of the matrin 3 protein family and has been shown to bind DNA consensus sequences and co-localize with PCNA during replication. In breast cancer cells, CIZ1 was shown to associate with Cdk2 and dynein light chain 1 (DLC1), a cytoskeletal signaling protein involved in cell cycle regulation and tumorigenesis. Studies of the role of CIZ1 in breast tumorigenesis revealed that CIZ1 is an estrogen-responsive gene that functions as a coactivator of the estrogen receptor. Targeted depletion of CIZ1 inhibits entry into S-phase. This finding along with evidence that CIZ1 interacts with multiple cell cycle regulatory proteins and localizes to DNA replication foci, indicates that CIZ1 plays a critical role in the regulation of DNA replication.
    基因ID
    25792
    NCBI登录号
    NP_036259
    UniProt
    Q9ULV3
    途径
    Maintenance of Protein Location
You are here:
客服